Bio- and Bioinspired Nanomaterials -- Contents -- List of Contributors -- Foreword -- Preface -- Part I: Bionanomaterials -- 1 Synthesis of Colloidal Gold and Silver Nanoparticles and their Properties -- 1.1 Introduction -- 1.2 Physical and Chemical Properties of Gold and Silver Nanoparticles -- 1.2.1 Optical Properties of Gold and Silver Nanoparticles -- 1.2.2 Electronic Properties of Gold and Silver Nanoparticles -- 1.3 Synthesis of Gold and Silver Core Nanoparticles -- 1.4 Transfer to Aqueous Media of Gold and Silver Nanoparticles from Organic Solvents -- 1.5 Some Applications of Gold and Silver Nanoparticles -- Acknowledgments -- References -- 2 Ceramic Smart Drug Delivery Nanomaterials -- 2.1 Introduction -- 2.2 Biodistribution, Toxicity, and Excretion of Nanoparticles -- 2.3 Mesoporous Silica Nanoparticles -- 2.4 Calcium Phosphate Nanoparticles -- 2.5 Carbon Allotropes -- 2.6 Iron Oxide Nanoparticles -- References -- 3 Polymersomes and their Biological Implications -- 3.1 Introduction -- 3.2 Self-Assembly of Amphiphiles -- 3.3 Polymersome - The Synthetic Analog of a Liposome -- 3.3.1 Polymersome Preparation Methods -- 3.3.1.1 Batch Methods -- 3.3.1.2 Continuous Flow Methods -- 3.3.2 Characterization of Polymersomes -- 3.4 Polymersomes as Drug Delivery Devices -- 3.4.1 Tuning Membrane Properties and Controlling the Release -- 3.4.1.1 pH-Responsive Polymersomes -- 3.4.1.2 Hydrolysis of Polymersomes Built from Biodegradable Polymers -- 3.4.1.3 GSH-Responsive (Redox) Vesicles -- 3.4.1.4 Temperature-Responsive Polymers -- 3.4.1.5 Magnetic Release -- 3.4.2 Surface Functionalization and Targeting Strategies -- 3.5 Embedding Channel Proteins in Artificial Polymer Membranes and Creating New Applications -- 3.6 Conclusions and Outlook -- List of Abbreviations -- References -- 4 MOFs in Pharmaceutical Technology -- 4.1 Introduction.

4.2 Metal-Organic Frameworks -- 4.2.1 Description -- 4.2.2 Synthesis, Formulation, and Functionalization/Shaping -- 4.2.2.1 Synthesis and Formulation/Shaping -- 4.2.2.2 Functionalization -- 4.2.3 Stability and Toxicity -- 4.3 MOFs for Therapeutics -- 4.3.1 BioMOFs -- 4.3.2 Active Ingredient Adsorption and Release from MOFs -- 4.3.2.1 Drugs -- 4.3.2.2 Cosmetics -- 4.3.3 Understanding -- 4.3.3.1 Encapsulation -- 4.3.3.2 Release -- 4.3.4 Theranostics -- 4.3.5 Efficacy -- 4.4 Conclusions -- List of Abbreviations -- References -- 5 Amorphous Coordination Polymer Particles for Biomedicine -- 5.1 Introduction -- 5.2 Interaction of Nanoplatforms with the Biological Environment -- 5.3 CPPs as Realistic Alternative to Classical Nanosystems -- 5.3.1 Encapsulation Systems Based on CPPs -- 5.3.2 Active Metal-Organic Units -- 5.3.2.1 Active Metal Ions -- 5.3.2.2 Drugs as Bridging Ligands -- 5.3.2.3 Active Complexes -- 5.3.3 Smart Delivery Systems -- 5.3.4 Bioimaging -- 5.3.5 Biocompatibility of CPPs -- 5.4 Conclusion and Future Challenges -- References -- 6 Magnetic Nanoparticles for Magnetic Hyperthermia and Controlled Drug Delivery -- 6.1 Introduction -- 6.2 Principles of Magnetically Induced Heat Generation -- 6.3 Synthesis of MNPs and their Heat Performance -- 6.3.1 Coprecipitation Method -- 6.3.2 Thermal Decomposition Method -- 6.4 Local Heating and Induced Biological and Drug Release Effects -- 6.5 In Vivo Drug Release from Magnetic Hybrid Systems Under Alternating Magnetic Field Exposure -- References -- 7 Photothermal Effect of Gold Nanostructures for Application in Bioimaging and Therapy -- 7.1 Introduction -- 7.2 Photophysical Characterization of Gold Nanostructures -- 7.2.1 Photophysical Behavior of Gold Nanostructures -- 7.2.2 Plasmonic Photothermal Effect -- 7.3 Tuning the Absorption Spectrum of Gold Nanostructures -- 7.3.1 Nanoparticles.

7.3.2 Nanoshells -- 7.3.3 Nanorods -- 7.3.4 Other Types of Nanostructures -- 7.4 Plasmonic Photothermal Effect of GNS in Imaging -- 7.4.1 Photoacoustic Imaging -- 7.4.2 Photothermal Imaging -- 7.4.3 Photothermal Treatments or Manipulation -- 7.4.3.1 Hyperthermia -- 7.4.3.2 Photothermal Ablation -- 7.5 Concluding Remarks -- Acknowledgment -- List of Abbreviations -- References -- 8 Nanomaterial-Based Bioimaging Probes -- 8.1 Introduction -- 8.2 Nanoprobes -- 8.3 Imaging Probes -- 8.4 Targeting Strategies -- 8.4.1 Passive Targeting -- 8.4.2 Active Targeting -- 8.4.3 Limitations -- 8.5 Nanotheranostics -- 8.6 Design Considerations -- 8.7 Summary and Future Trends -- References -- 9 Molecular Bases of Nanotoxicology -- 9.1 Introduction -- 9.2 Impact on Environment: Nanoecotoxicology -- 9.3 Impact on Health: Nanotoxicology -- 9.3.1 The Basis of Nanogenotoxicity: NPs Affect DNA Integrity and Stability -- 9.3.2 Hallmarks of gene Expression in Response to NPs -- 9.3.3 New Frontiers in Nanotoxicology: Nanomaterials Drive Epigenetic Changes -- References -- Part II: Bioinspired Materials - Bioinspired Materials for Technological Application -- 10 Bioinspired Interfaces for Self-cleaning Technologies -- 10.1 The Concept of Bioinspiration in Materials Engineering -- 10.1.1 Terms -- 10.1.2 Bioinspiration and Nanotechnology -- 10.2 Basics of Wetting -- 10.2.1 Contact Angle and Contact Angle Hysteresis -- 10.2.2 Contact Angle on Rough Surfaces -- 10.3 Self-cleaning Technologies -- 10.3.1 Fluid Transport -- 10.3.2 Biofouling -- 10.3.3 Water, Oil, and Stain Repellency -- 10.4 Summary -- References -- 11 Catechol-Based Biomimetic Functional Materials and their Applications -- 11.1 Introduction -- 11.2 Adhesives -- 11.2.1 General Purpose Adhesives -- 11.2.2 Adhesive Hydrogels for Biomedical Applications.

11.3 Functionalizable Platforms (Primers) on Macroscopic Surfaces -- 11.3.1 Polydopamine -- 11.3.1.1 Bio- and Biomedical Applications -- 11.3.1.2 Hydrophobic/Hydrophilic Coatings -- 11.3.2 Other Catechol-Containing Polymers -- 11.3.2.1 Antifouling Coatings -- 11.3.2.2 Antibacterial Coatings -- 11.3.2.3 Anti-corrosion -- 11.3.2.4 Hydrophobic/Hydrophilic Coatings -- 11.4 Micro-/Nanoscopic Surface Functionalization -- 11.4.1 Catechol-Modified Ferric NPs -- 11.4.1.1 Therapeutic Uses and Imaging -- 11.4.1.2 Biosensors -- 11.4.2 Functionalization of Nano- and Microstructures Other than Fe3O4 NPs -- 11.5 Functional Scaffolds -- 11.5.1 Oriental Lacquers -- 11.5.2 Melanin -- 11.5.3 Polydopamine-Based Nanoparticles -- 11.6 Chelating Materials/Siderophore-Like Materials -- 11.6.1 Therapeutic Uses and Imaging -- 11.6.2 Heavy Metal Scavenging -- 11.7 Materials for Chemo-/Biosensing -- 11.8 Electronic Devices -- 11.8.1 Molecular Electronics -- 11.8.2 Dye-Sensitized Solar Cells -- 11.8.3 Miscellaneous Devices -- References -- 12 Current Approaches to Designing Nanomaterials Inspired by Mussel Adhesive Proteins -- 12.1 Introduction -- 12.2 Mussel Adhesive Proteins and DOPA -- 12.2.1 Catechol Side Chain Chemistry -- 12.2.1.1 Reversible Physical Interactions -- 12.2.1.2 Oxidation-Mediated Crosslinking -- 12.3 Nanoparticle Stabilization -- 12.3.1 Grafting Catechol-Polymer Conjugate -- 12.3.2 Surface-Initiated Polymerization -- 12.3.3 Chemical Modification of Catechol Side Chain -- 12.4 Nanocomposite Materials -- 12.4.1 Nanocomposite Hydrogel -- 12.4.2 LbL Nanocomposite Films -- 12.4.3 Nanocomposite Fiber -- 12.4.4 Nanocomposite Rubber -- 12.5 Gecko and Mussel Dual Mimetic Adhesive -- 12.6 Polydopamine as a Multifunctional Anchor -- 12.6.1 Polydopamine-Mediated Hierarchical Surface Modification -- 12.6.2 Polydopamine-Coated Nanoparticles for Therapeutic Applications.

12.7 Summary and Future Outlook -- Acknowledgment -- References -- Part III: Bioinspired Materials - Bioinspired Materials for Biomedical Applications -- 13 Functional Gradients in Biological Composites -- 13.1 Introduction -- 13.2 Chemical Gradient -- 13.3 Hydration Gradient -- 13.4 Mineral Gradient -- 13.5 Texture Gradient -- 13.6 Porosity Gradient -- 13.7 Conclusions -- References -- 14 Novel Bioinspired Phospholipid Polymer Biomaterials for Nanobioengineering -- 14.1 Introduction -- 14.2 Molecular Design of an Artificial Cell Membrane Surface -- 14.3 Polymer Nanoparticles System with an Artificial Cell Membrane Structure -- 14.3.1 Preparation of Polymer Nanoparticles with an Artificial Cell Membrane Structure -- 14.3.2 Functionality of Biomolecules Immobilized on an Artificial Cell Membrane Surface -- 14.3.3 Multiple Functions of the Artificial Cell Membrane Structure -- 14.4 Nanomaterials Entrapped in the Polymeric Nanoparticles with an Artificial Cell Membrane -- 14.4.1 Surface Modification of Quantum Dots (QDs) with Phospholipid Polymers -- 14.4.2 Encapsulation of QDs in the Polymeric Nanoparticles Covered with Artificial Cell Membrane -- 14.4.3 In-Cell Performance of Polymeric Nanoparticles Covered with Artificial Cell Membrane -- 14.5 Future Perspectives -- List of Abbreviations -- References -- 15 Bioinspired Functionalized Nanoparticles as Tools for Detection, Quantification and Targeting of Biomolecules -- 15.1 Introduction -- 15.2 Bioinspired Functionalized Nanoparticles -- 15.2.1 Bioinspired Probes and Nanoparticle Functionalization -- 15.3 Biomedical Applications -- 15.3.1 In Vitro Diagnostics Using Nanoparticles -- 15.3.1.1 Detection of Biomolecules -- 15.3.1.2 Detection of Tumor Cells: Bioimaging -- 15.3.1.3 Separation and Purification of Biological Molecules and Cells -- 15.3.1.4 Biodetection of Pathogens.

15.4 Therapeutics Applications of Nanoparticles.