Cover image for The chemistry of C-glycosides
The chemistry of C-glycosides
Title:
The chemistry of C-glycosides
Author:
Levy, D. E. (Daniel E.)
ISBN:
9780080420806
Personal Author:
Edition:
1st ed.
Publication Information:
Oxford, OX, U.K. ; Tarrytown, N.Y., U.S.A. : Pergamon, 1995.
Physical Description:
xiv, 291 p. : ill. ; 26 cm.
Series:
Tetrahedron organic chemistry series ; v. 13
Series Title:
Tetrahedron organic chemistry series ; v. 13
Contents:
Introduction. Electrophilic Substitutions. Nucleophilic Sugar Substitutions. Transition Metal Mediated C-Glycosidations. Anomeric Radicals. Rearrangements and Cycloadditions. Sugar Ring Formations. Syntheses of C-Di and Trisaccharides. Index.
Abstract:
In recent years C-glycoside chemistry has been one of the main topics in carbohydrate chemistry, not only because of the synthetic challenges posed, but also because C-glycosides have the potential to serve as carbohydrate analogues resistant to metabolic processes. Consequently, this class of compounds is currently receiving much interest as a potential source of therapeutic agents for clinical use. This book provides a broad coverage of the various synthetic methods available for the preparation of C-glycosides, and illustrates the interesting breadth of connections between carbohydrate chemistry and modern general synthetic organic chemistry by including topics such as transition-metal catalysis, radical chemistry, cycloaddition and rearrangement processes. In addition, in the final chapter of the book, the syntheses of C-di and trisaccharides reported through 1994 are reviewed. This well organised account of the synthetic chemistry in this field will prove to be very valuable to a wide range of researchers and advanced students, both as an introduction to the topic and for reference.
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