A Review of the Department of Defense's Program for Breast Cancer Research -- Copyright -- Preface -- Contents -- Executive Summary -- CHARGE TO THE COMMITTEE -- THE ARMY'S BREAST CANCER RESEARCH PROGRAM -- METHODS -- FINDINGS -- The Army's Breast Cancer Research Program Operation -- The Breast Cancer Research Program Portfolio -- Support for Breast Cancer Research Other Than the Army's Program -- Research Advances and Opportunities -- CONCLUSIONS -- RECOMMENDATIONS RELATED TO PROGRAM ACHIEVEMENT AND MANAGEMENT -- RECOMMENDATIONS FOR FUTURE RESEARCH DIRECTIONS -- 1 Introduction -- THE ARMY BREAST CANCER RESEARCH PROGRAM -- CHARGE TO THE 1997 IOM COMMITTEE -- RESOURCES AND METHODS USED FOR THIS REPORT -- 2 Breast Cancer: Biology and Medicine -- INCIDENCE AND MORTALITY -- STAGES OF BREAST CANCER DEVELOPMENT -- BREAST CANCER GENETICS -- OTHER RISK FACTORS -- BREAST IMAGING, TREATMENT, AND PREVENTION -- Breast Imaging -- Treatment -- Prevention -- SOCIAL AND PSYCHOLOGICAL ASPECTS -- 3 Non-BCRP Support for Breast Cancer Research -- PUBLISHED LITERATURE -- FUNDING FROM THE FEDERAL GOVERNMENT -- Non-BCRP Department of Defense Programs -- Other Federal Entities (Excluding Department of Health and Human Services) -- Department of Health and Human Services -- The National Cancer Institute -- Other NIH Institutes -- Other DHHS Agencies -- National Action Plan on Breast Cancer -- THE CALIFORNIA BREAST CANCER RESEARCH PROGRAM -- PRIVATE FOUNDATIONS -- American Cancer Society -- Susan G. Komen Foundation -- Other Philanthropic Organizations -- NATIONAL PROFESSIONAL ORGANIZATIONS AND SOCIETIES -- PHARMACEUTICAL INDUSTRY -- 4 U.S. Army Breast Cancer Research Program -- HISTORICAL OVERVIEW -- IOM PROGRAMMATIC VISION (1993) -- Two-Tiered Review Process -- Program Administration and Management -- BCRP IMPLEMENTATION, 1993-1996 -- Scientific Oversight.

The Integration Panel -- Executive Committee -- Programmatic Goals -- THE REVIEW PROCESS -- Tier 1: Scientific Peer Review -- Tier 2: Programmatic Review -- Consumer Participation -- Award Negotiation and Processing -- Monitoring and Evaluation of Progress -- 5 The Funded Portfolio of the 1993/1994 and 1995 BCRP Award Cycles -- RESEARCH PROJECTS -- INFRASTRUCTURE ENHANCEMENT -- TRAINING AND RECRUITMENT -- Breast Cancer Centers and Mammography/Breast Imaging Projects -- Historically Black Colleges and Universities/Minority Institutions -- Opportunities for Minorities and Women -- FUNDING FOR PROGRAM ADMINISTRATION -- DISTRIBUTION OF AWARDS AMONG RESEARCH AREAS -- 6 Critique -- ORGANIZATIONAL STRUCTURE AND PROGRAM OVERSIGHT -- APPLICATION PROCESS -- SCIENTIFIC PEER REVIEW -- PROGRAMMATIC REVIEW -- AWARD NEGOTIATION AND PROCESSING -- MONITORING AND EVALUATION OF PROGRESS -- CONSUMER PARTICIPATION -- FUNDED PORTFOLIO -- 7 Conclusions and Recommendations -- CONCLUSIONS -- RECOMMENDATIONS RELATED TO PROGRAM ACHIEVEMENT AND MANAGEMENT -- Major Recommendations -- Other Recommendations -- RECOMMENDATIONS FOR FUTURE RESEARCH DIRECTIONS -- References -- APPENDIX A Individuals Who Provided Testimony to the Committee -- USAMRMC -- BCRP SUPPORT -- BREAST CANCER FUNDING INSTITUTIONS -- PEER REVIEW ORGANIZATIONS -- BCRP EXECUTIVE SECRETARIES -- CONSUMER ORGANIZATIONS/ADVOCACY GROUPS -- INTEGRATION PANEL MEMBERS -- OTHER IOM STAFF -- APPENDIX B Individuals Who Provided Written Responses to Committee Questions -- PROFESSIONAL SOCIETIES -- EXECUTIVE SECRETARIES -- CONSUMER GROUPS -- APPENDIX C ''Dear Colleague" Letter -- APPENDIX D Responses to "Dear Colleague" Letter -- APPENDIX E Tissue Bank Letter and Questionnaire -- Glossary and Acronyms -- Biographical Sketches.