Quality of Life and Technology Assessment -- Copyright -- Acknowledgments -- Preface -- Contents -- 1 Conceptual Background and Issues in Quality of Life -- CONCEPTUAL BACKGROUND -- A Continuum of Health-Related Measures -- Health Status -- Quality-of-Life Measures -- ISSUES RELATING TO SELECTING HEALTH AND QUALITY-OF-LIFE MEASURES -- REFERENCES -- 2 The Use of Quality-of-Life Measures in Technology Assessment -- LITERATURE REVIEWS -- Study Design -- Not Reinventing the Wheel -- THE VALUE OF ASSESSING QUALITY OF LIFE AS AN OUTCOME -- Work Status -- DIAGNOSIS-AN OPEN PROBLEM -- ROLES OF THE EXAMPLES -- TWELVE APPLICATIONS OF QUALITY-OF-LIFE MEASURES TO TECHNOLOGY ASSESSMENT -- Study 1. Antihypertensive Medications -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 2. Arthritis Medications -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 3. Adjuvant Chemotherapy -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 4. Alternative Chemotherapy Regimens in Advanced Breast Cancer -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 5. Counseling for Stage IV Cancer -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 6. Surgery for Breast Cancer -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 7. Cardiac Transplant and Coronary Artery Bypass Graft Surgery -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 8. Cardiac Rehabilitation Programs -- Key -- Description of Measures -- Purpose of the Study.

Methods -- Results and Conclusions -- Comments -- Study 9. Long-term Dialysis and Renal Transplant -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 10. Renal Transplantation and Dialysis -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 11. Case Management and Usual and Customary Services for Chronically Mentally Ill Patients -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- Study 12. Health Insurance Payment Mechanisms -- Key -- Description of Measures -- Purpose of the Study -- Methods -- Results and Conclusions -- Comments -- REFERENCES -- 3 Quality-of-Life Measures in Liver Transplantation -- QUALITY-OF-LIFE MEASURES -- Alterations in Neuropsychiatric Testing -- Ability to Return to Work, School, or Prior Social Situation -- Presence of Psychopathology -- Scores on Specific Quality-of-Life Questionnaires -- CONCLUSIONS -- REFERENCES -- 4 Quality-of-Life Measures and Methods Used to Study Antihypertensive Medications -- REFERENCES -- 5 The Use of Quality-of-Life Measures in the Private Sector -- METHOD OF STUDY -- Private-Sector Research in Quality of Life -- Food and Drug Administration Perspective -- Private Industry Perspective -- RESULTS OF THE QUALITY-OF-LIFE SURVEY -- Pharmaceutical Industry -- Medical Device Companies -- CONCLUSIONS -- REFERENCES -- SELECTED FURTHER READING -- 6 Assessing Quality of Life: Measures and Utility -- ISSUES IN SELECTING QUALITY-OF-LIFE MEASURES -- Disease-Specific Versus Global Assessments -- Clinical Endpoints Versus Long-Term Outcomes -- Patient Ratings Versus Proxy Assessments -- Objective Versus Subjective Measures -- Cognitive Functioning -- Ratings and Utilities -- Timing of the Assessments -- Summary.

STRATEGIES USED TO ASSESS INSTRUMENTS -- Reliability -- Validity -- A REVIEW OF SELECTED MEASURES FOR ASSESSING QUALITY OF LIFE -- A REVIEW OF UTILITY ASSESSMENTS IN QUALITY OF LIFE -- THREE SOURCES OF DESCRIPTIVE INFORMATION FOR QUALITY-OF-LIFE MEASURES -- TEN REVIEW FORMS FOR QUALITY-OF-LIFE MEASURES -- 1. Review Form for Quality of Life Index and Quality of Life Uniscale -- Primary References: -- References and Applications: -- 2. Review Form for Life Situation Survey -- Primary Reference: -- References: -- 3. Review Form for Quality of Life Index -- Primary Reference: -- Reference: -- 4. Review Form for the Quality of Life Index for Colostomy Patients -- Primary Reference: -- Reference: -- 5. Review Form for Quality of Life Index -- Primary Reference: -- Reference: -- 6. Review Form for Karnofsky Index of Performance Status (KPS) -- Primary Reference: -- References: -- 7. Review for Functional Living Index-Cancer -- Primary Reference: -- References and Applications: -- 8. Review Form for Selby et al.'s Quality of Life Measure -- Primary Reference: -- References and Applications: -- 9. Review Form for Linear Analogue Self-Assessment -- Primary References: -- References and Applications: -- 10. Review Form for Breast Cancer Chemotherapy Questionnaire -- Primary Reference: -- REFERENCES -- 7 Applications of Quality-of-Life Measures and Areas for Cooperative Research -- REFERENCE -- The Authors.