Tempo And Mode In Evolution -- Copyright -- PREFACE -- REFERENCES -- Contents -- PART I EARLY LIFE -- 1 Tempo, Mode, the Progenote, and the Universal Root -- STAGES IN THE EVOLUTION OF THE CELLULAR INFORMATION-PROCESSING SYSTEM -- THE BASIC KINDS OF LIVING THINGS -- THE WOESIAN REVOLUTION -- ROOTING THE UNIVERSAL TREE -- IMPLICATIONS OF THE ROOTING FOR AN UNDERSTANDING OF TEMPO AND MODE IN EARLY CELLULAR EVOLUTION -- But Is the Rooting Right? -- Where Next? -- SUMMARY -- References -- 2 Phylogeny from Function: The Origin of tRNA Is in Replication, not Translation -- METHODS -- RESULTS AND DISCUSSION -- CONCLUSIONS AND FUTURE PROSPECTS -- SUMMARY -- References -- 3 Disparate Rates, Differing Fates: Tempo and Mode of Evolutionm Changed from the Precambrian to the Phanerozoic -- TEMPOS OF EVOLUTION -- CYANOBACTERIAL HYPOBRADYTELY -- SURVIVAL OF THE ECOLOGICALLY UNSPECIALIZED -- A BIPARTITE VIEW OF THE HISTORY OF LIFE -- SUMMARY -- References -- 4 Proterozoic and Early Cambrian Protists: Evidence for Accelerating Evolutionary Tempo -- THE NATURE AND LIMITATIONS OF THE RECORD -- EARLY EUKARYOTIC FOSSILS: A NARRATIVE RECORD -- ESTIMATES OF EVOLUTIONARY TEMPO -- DISCUSSION -- CONCLUSIONS -- SUMMARY -- References -- PART II MACROEVOLUTION -- 5 Late Precambrian Bilaterians: Grades and Clades -- APPEARANCE OF PHYLA IN THE FOSSIL RECORD -- THE RISE OF BODY-PLAN COMPLEXITY -- PHYLOGENETIC MODELS AND BODY PLANS -- TEMPO AND MODE AND BODY PLANS -- SUMMARY -- References -- 6 The Role of Extinction in Evolution -- CHARLES DARWIN ON EXTINCTION -- GEORGE GAYLORD SIMPSON ON EXTINCTION -- THE RECORD OF EXTINCTION -- EPISODES OF EXTINCTION -- SELECTIVITY -- CAUSES OF EXTINCTION -- THE ROLE OF EXTINCTION -- SUMMARY -- References -- 7 Tempo and Mode in the Macroevolutionary Reconstruction of Darwinism.

DARWIN'S UNIFORMITARIANISM AND THE DOWNGRADING OF MACROEVOLUTION -- TEMPO AND MODE: A POTENTIAL SOLUTION UNDERMINED -- A SOLUTION IN BONDED INDEPENDENCE -- SUMMARY -- REFERENCES -- 8 Morphological Evolution Through Complex Domains of Fitness -- PLANTS AS A VENUE FOR SIMULATED WALKS -- SINGLE- VERSUS MULTI-TASK WALKS -- WEAKNESSES AND STRENGTHS OF SIMULATED WALKS -- SUMMARY -- REFERENCES -- PART III HUMAN EVOLUTION -- 9 Tempo and Mode in Human Evolution -- SPECIES, CLADES, AND PHYLOGENY -- BIPEDALISM AND THE POSTCRANIUM -- MASTICATION -- ENCEPHALIZATION -- STASIS, PUNCTUATION, AND TRENDS -- SUMMARY -- References -- 10 Molecular Genetics of Speciation and Human Origins -- SPECIATION BY FOUNDER EFFECT -- THE MAJOR HISTOCOMPATIBILITY COMPLEX -- TRANS-SPECIFIC POLYMORPHISMS -- EVOLUTIONARY HISTORY OF THE DRB1 GENE LOCUS -- PERSISTENCE OF POLYMORPHISMS -- EVOLUTIONARY SUBSTITUTIONS AND COALESCENCE THEORY -- POPULATION BOTTLENECKS AND THE ORIGIN OF MODERN HUMANS -- THEORIES OF HUMAN ORIGINS -- MOLECULAR EVIDENCE AND THE MULTIREGIONAL MODEL -- SUMMARY -- REFERENCES -- PART IV RATES -- 11 Rates and Patterns of Chloroplast DNA Evolution -- EVOLUTION OF NONCODING DNA REGIONS -- EVOLUTION OF PROTEIN CODING GENES -- PATTERNS OF AMINO ACID REPLACEMENT IN THE RUBISCO PROTEIN -- PATTERNS OF INTRON EVOLUTION -- CONCLUSIONS -- SUMMARY -- References -- 12 The Superoxide Dismutase Molecular Clock Revisited -- METHODS -- RESULTS -- DISCUSSION -- SUMMARY -- References -- PART V PATTERNS -- 13 Dynamics of Adaptation and Diversification: A 10,000-Generation Experiment with Bacterial Populations -- EXPERIMENTAL OVERVIEW -- ANALYSES AND INTERPRETATION -- CONCLUSIONS AND DISCUSSION -- CODA -- SUMMARY -- References -- 14 Explaining Low Levels of DNA Sequence Variation in Regions of the Drosophila Genome with Low Recombination Rates -- THE DATA -- A STRICTLY NEUTRAL HYPOTHESIS.

HITCHHIKING WITH FAVORABLE MUTATIONS HYPOTHESIS -- BACKGROUND SELECTION MODEL -- DISCUSSION AND CONCLUSION -- SUMMARY -- References -- 15 The History of a Genetic System -- MATERIALS AND METHODS -- RESULTS AND DISCUSSION -- SUMMARY -- References -- 16 Genome Structure and Evolution in Drosophila: Applications of the Framework P1 Map -- MATERIALS AND METHODS -- RESULTS -- DISCUSSION -- SUMMARY -- References -- INDEX.