Future Biotechnology Research on the International Space Station -- Copyright -- Foreword -- Preface -- Acknowledgment of Reviewers -- Contents -- Executive Summary -- BACKGROUND AND SCIENTIFIC SCOPE OF NASA PROGRAMS -- Protein Crystal Growth -- Cell Science -- INSTRUMENTATION -- Protein Crystal Growth -- Cell Science -- Overall Volume Allotment for Biotechnology Research on the ISS -- SELECTION AND OUTREACH -- Protein Crystal Growth -- Cell Science -- 1 Background and Scientific Scope of NASA Programs -- INTRODUCTION -- PROTEIN CRYSTAL GROWTH -- The Significance of Crystallographic Resolution Limits -- Goals and History of the NASA Protein Crystal Growth Effort -- Results to Date: Examples of Successful Experiments and the Importance of Defining Controls -- Potential Areas of Future Impact -- Potential Benefits of the Space Station Platform -- Potential for Interest from Commercial Entities -- CELL SCIENCE -- Goals and Potential Impacts of the NASA Cell Science Effort -- Experimental Design and Instrumentation -- Requirements for Interprogrammatic Coordination Within NASA -- 2 Instrumentation -- LOGISTICS FOR USING THE INTERNATIONAL SPACE STATION AS A BIOTECHNOLOGY RESEARCH PLATFORM -- PROTEIN CRYSTAL GROWTH -- The Hardware Development Process -- Key Characteristics of Protein Crystal Growth Hardware on the ISS -- The X-ray Crystallography Facility -- CELL SCIENCE -- Cell and Tissue Culture Hardware -- Experiment Management -- Storage, Transport, and Throughput of Samples -- OVERALL VOLUME ALLOTMENT FOR BIOTECHNOLOGY RESEARCH ON THE ISS -- 3 Selection and Outreach -- SELECTION PROCESS, OUTREACH EFFORTS, AND COMMUNICATION AMONG PROGRAM PARTICIPANTS -- Improving the Dissemination of NRAs and NASA Program Results -- Improving the Selection Process -- Improving Connections to Relevant Communities and Attracting the Best Science.

Coordination: Investigators and Operations Personnel -- PROTEIN CRYSTAL GROWTH -- The Guest Investigator Program -- Funding Research on Biologically Challenging Problems -- CELL SCIENCE -- Cooperation with NASA's Life Sciences Division and with Other Federal Agencies -- Resource Management and Communication in Times of Crisis -- Bibliography -- Appendixes -- A Hardware Available or in Development and Schedule for Biotechnology Research on the International Space Station -- HARDWARE FOR PROTEIN CRYSTAL GROWTH IN SPACE -- Basic Apparatus to House Protein Crystal Growth Hardware -- Protein Crystal Growth Hardware -- Devices in Fabrication for in Situ Observation of Crystallization on Orbit -- Devices in Early Definition Phase for in Situ Observation of Crystallization on Orbit -- X-ray Crystallography Facility -- Relevant Support Equipment -- HARDWARE FOR CELL SCIENCE IN SPACE -- Cell and Tissue Culture Hardware in Development for ISS -- Cell Science Support Equipment -- General Support Equipment Relevant to Cell Science Research -- Analytical Equipment -- Miscellaneous -- SCHEDULE -- B Biographical Sketches of Task Group Members -- C Statement of Task -- D Glossary -- E Acronyms and Abbreviations.