TOXICOLOGIC ASSESSMENT OF THE ARMY'S ZINC CADMIUM SULFIDE DISPERSION TESTS -- Copyright -- OTHER RECENT REPORTS OF THE BOARD ON ENVIRONMENTAL STUDIES AND TOXICOLOGY -- OTHER RECENT REPORTS OF THE COMMITTEE ON TOXICOLOGY -- PREFACE -- Contents -- SUMMARY -- TASKS OF THE SUBCOMMITTEE -- SOURCES OF INFORMATION -- INPUT FROM THE PUBLIC -- OPEN LITERATURE AND UNPUBLISHED REPORTS -- CONCLUSIONS -- PHYSICAL AND CHEMICAL PROPERTIES -- TOXICOKINETICS AND BIOAVAILABILITY OF ZNCDS: AVAILABILITY OF CADMIUM FROM ZNCDS -- TOXICITY -- TOXICITY OF SELECTED CADMIUM COMPOUNDS -- EXPOSURE ASSESSMENT -- RISK ASSESSMENT OF ZNCDS EXPOSURES -- SCIENTIFIC FEASIBILITY OF EPIDEMIOLOGIC STUDY -- RECOMMENDATIONS -- 1 INTRODUCTION -- ZNCDS DISPERSION TESTS -- PUBLIC CONCERN IN RESPONSE TO ZNCDS DISPERSION TESTS -- TASKS OF THE SUBCOMMITTEE -- SOURCES OF DATA -- STRUCTURE OF THE REPORT -- 2 INPUT FROM THE PUBLIC -- NATURE OF COMMENTS -- SPECIFIC HEALTH PROBLEMS -- CONCLUSIONS -- 3 TOXICITY AND RELATED DATA ON ZINC CADMIUM SULFIDE -- PHYSICAL AND CHEMICAL PROPERTIES -- TOXICOKINETICS AND BIOAVAILABILITY OF ZNCDS: AVAILABILITY OF CADMIUM FROM ZNCDS -- TOXICITY -- IMPLICATIONS OF VARIABLE COMPOSITION -- CONCLUSIONS AND RECOMMENDATIONS -- 4 TOXICITY AND RELATED DATA ON SELECTED CADMIUM COMPOUNDS -- PHYSICAL AND CHEMICAL PROPERTIES OF CADMIUM COMPOUNDS -- TOXICOKINETICS OF CADMIUM COMPOUNDS -- INSOLUBLE CADMIUM COMPOUNDS -- SOLUBLE CADMIUM COMPOUNDS -- TOXICITY OF CADMIUM COMPOUNDS -- NONCANCER EFFECTS -- IN VIVO INSOLUBLE CADMIUM COMPOUNDS -- IN VIVO SOLUBLE CADMIUM COMPOUNDS -- GENOTOXICITY OF CADMIUM COMPOUNDS -- CARCINOGENICITY OF CADMIUM COMPOUNDS -- LUNG CANCER -- PROSTATIC CANCER -- OTHER CANCERS -- CONCLUSIONS -- 5 EXPOSURE ASSESSMENT -- ZINC CADMIUM SULFIDE -- CADMIUM -- CONCLUSIONS -- 6 RISK CHARACTERIZATION OF EXPOSURES TO ZINC CADMIUM SULFIDE.

RISK ASSESSMENT FOR NONCANCER HEALTH EFFECTS -- RISK ASSESSMENT FOR CANCER -- LUNG-CANCER POTENCY OF CADMIUM -- LUNG-CANCER RISK ESTIMATES -- UNCERTAINTY OF LUNG-CANCER RISK ESTIMATES -- OTHER ROUTES OF EXPOSURE -- CONCLUSIONS -- 7 SCIENTIFIC FEASIBILITY OF EPIDEMIOLOGIC STUDY -- NATURE OF EPIDEMIOLOGIC INVESTIGATIONS -- KEY METHODOLOGIC ISSUES -- TYPES OF EPIDEMIOLOGIC STUDIES -- CONCLUSIONS -- 8 CONCLUSIONS AND RECOMMENDATIONS -- INPUT FROM THE PUBLIC -- TOXICITY AND RELATED DATA ON ZINC CADMIUM SULFIDE -- TOXICITY AND RELATED DATA ON SELECTED CADMIUM COMPOUNDS -- EXPOSURE ASSESSMENT -- RISK ASSESSMENT OF ZNCDS EXPOSURES -- FEASIBILITY OF EPIDEMIOLOGIC STUDY -- RECOMMENDATIONS -- REFERENCES -- APPENDIX A HISTORICAL BACKGROUND OF THE U.S. BIOLOGIC-WARFARE PROGRAM -- APPENDIX B SUMMARY OF DOSES AND CONCENTRATIONS OF ZINC CADMIUM SULFIDE PARTICLES FROM THE ARMY'S DISPERSION TESTS -- APPENDIX C CORRESPONDENCE FROM THE ARMY -- APPENDIX D INTERACTION OF ZINC AND CADMIUM AND TOXICITY OF ZINC CADMIUM SULFIDE ACTIVATORS -- APPENDIX E PUBLIC MEETING AGENDAS -- APPENDIX F SAMPLING AND ANALYTIC METHODS FOR ZINC CADMIUM SULFIDE -- APPENDIX G REVIEW OF AEHA RISK-ASSESSMENT REPORTS ON ZINC CADMIUM SULFIDE -- APPENDIX H REVIEW OF EPA, ATSDR, AND CDC COMMENTS ON THE ARMY'S RISK-ASSESSMENT REPORTS ON ZINC CADMIUM SULFIDE -- APPENDIX I CADMIUM EXPOSURE ASSESSMENT, TRANSPORT, AND ENVIRONMENT FATE -- Glossary.