Contents -- Preface -- List of abbreviations -- Executive Summary -- Sammenfatning -- 1 Introduction -- 1.1 Background and definition -- 1.2 OECD for the Testing and Assessment of Endocrine Disrupting Chemicals -- 1.3 EU Chemicals Policy -- 1.4 Globally Harmonised System of classification and labelling of chemicals (GHS) -- 1.5 Aim of the project -- 2 Conceptual Framework - with specific focus on l -- 2.1 Introduction -- 2.2 Level 2, in vitro assays providing mechanistic data -- 2.3 Level 3, Short terms in vivo assays providing data about single endocrine mechanisms and effects -- 2.4 Level 4, male and female pubertal assays, intact male assay, and enhanced OECD TG 407 (28-day toxicity study) providing in vivo data about multiple endocrine mechanisms and effects -- 2.5 Level 5, in vivo assays providing adverse effect data from endocrine and other mechanisms -- 3 Specific chemicals and observed ED-effects -- 3.1 Comparison of LO(A)ELs in EDC assays -- 3.2 Discussion and conclusions -- 4 Discussion and conclusions -- 4.1 Summary on the assays at level 2 to 5 and regulatory proposals -- 4.2 Enhancement of existing OECD TG -- 4.3 Hazard classification for EDC effects and authorisation -- 5 References -- 6 Appendix.