Cover image for Arrhythmogenic RV Cardiomyopathy/Dysplasia Recent Advances
Arrhythmogenic RV Cardiomyopathy/Dysplasia Recent Advances
Title:
Arrhythmogenic RV Cardiomyopathy/Dysplasia Recent Advances
Author:
Markus, Frank I. editor.
ISBN:
9788847004900
Physical Description:
XIII, 217 p. online resource.
Contents:
Introduction: Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia Clarified -- Advances in Genetics: Dominant Forms -- Advances in Genetics: Recessive Forms -- Genotype-Phenotype Correlations -- Autopsy and Endomyocardial Biopsy Findings -- Cell Adhesion Pathology -- Ultrastructural Substrates -- Transgenic Animal Models -- Spontaneous Animal Models -- Possible Causative or Contributing Role of Viruses -- Diagnosis: Task Force Criteria including Modifications for Family Members -- Strengths and Weaknesses of the Task Force Criteria — Proposed Modifications -- Idiopathic Right Ventricular Outflow Tract Tachycardia -- Electrocardiographic Manifestations -- Echocardiography -- MR and CT Imaging -- Diagnostic Role of Angiography -- Electrophysiologic Study including Electroanatomic Mapping -- Risk Stratification and Antiarrhythmic Drug Therapy -- Catheter Ablation of Ventricular Tachycardia -- The Role of the Implantable Cardiac Defibrillator in the Management -- Management of Heart Failure -- Sudden Death in Young Athletes.
Abstract:
This book covers all aspects (biological, pathological, genetic, clinical and therapeutical) of arrhythmogenic right ventricular cardiomyopathy/dysplasia, a recent cardiomyopathy which represents a very high risk of sudden death in the young and in athletes. The monograph presents the results of 5-year research program on ARVC/D supported by grants of both the European Commission and the NIH, which enabled the discovery of seven disease-causing genes, thus opening new avenues for the early identification of affected patients and for sudden death prevention. A panel of top scientists, both European and Americans, contributed to this volume, which will be an essential reference for professionals and residents in cardiology, radiology, human genetics, and sport medicine.
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