Part I: Essential pathology - mechanisms of disease: Molecular mechanisms of cell death -- Acute and chronic inflammation -- Infection and host response -- Neoplasia -- Part II: Concepts in molecular biology and genetics: Basic concepts in human molecular genetics -- The human genome: implications for the understanding of human disease -- The human transcriptome: implications for the understanding of human disease -- The human epigenome: implications for the understanding of human disease -- The human proteome: implications for the understanding of human disease -- Integrative systems biology: implications for the understanding of human disease -- Part III: Principles and practice of molecular pathology: Pathology: the clinical description of human disease -- Molecular pathogenesis: the biological basis of human disease -- Integration of molecular and cellular pathogenesis -- Part IV: molecular pathology of human disease: Molecular basis of cardiovascular disease -- Molecular basis of hemostatic and thrombotic diseases -- Molecular basis of lymphoid and myeloid diseases -- Molecular basis of diseases of immunity -- Molecular basis of pulmonary disease -- Molecular basis of diseases of the gastrointestinal tract -- Molecular basis of liver disease -- Molecular basis of diseases of the exocrine pancreas -- Molecular basis of diseases of the endocrine system -- Molecular basis of gynecologic diseases -- Molecular basis of prostate disease -- Molecular basis of breast disease -- Molecular basis of skin disease -- Molecular basis of diseases of the nervous system -- Part V: Practice of molecular medicine: Molecular diagnosis of human disease -- Molecular assessment of human disease in the clinical laboratory -- Pharmacogenomics and personalized medicine in the treatment of human disease.