Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment
Title:
Strategies to Enhance the Therapeutic Ratio of Radiation as a Cancer Treatment
Author:
Anscher, Mitchell S. editor.
ISBN:
9783319455945
Physical Description:
VI, 305 p. 65 illus., 53 illus. in color. online resource.
Contents:
1. Mechanisms of Normal Tissue Response -- 2. The Role of Hypoxia in Radiation Response -- 3. The Role of Cancer Stem Cells in Tumour Radioresponse -- 4. Novel Strategies to Prevent, Mitigate or Reverse Radiation Injury and Fibrosis -- 5. Technology Based Strategies to Enhance the Therapeutic Ratio -- 6. Nitric Oxide Synthase Uncoupling in Tumor Progression and Cancer Therapy -- 7. Aiming the Immune System to Improve the Antitumor Efficacy of Radiation Therapy -- 8. The Role of MicroRNAs in modulating Tissue Response to Radiation -- 9. Adapting Therapy Based on Tumor Response -- 10. NQO1 Bioactivatable Drugs Modify Radiation Responses -- 11. DNA Repair Pathways as a Potential Target for Radiosensitization -- 12. Radiosensitizing Glioma by Targeting ATM with Small Molecule Inhibitors.
Abstract:
This volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.
Added Corporate Author:
Electronic Access:
https://doi.org/10.1007/978-3-319-45594-5