Cover -- Disclaimer and acknowledgements -- Contents -- Tables -- Figures -- Abbreviations -- Part 1: Introduction -- Overview of the Global Burden of Disease Study -- What is new in this update for 2004? -- Regional estimates for 2004 -- Part 2: Causes of death -- 1. Deaths in 2004: who and where? -- 2. Deaths by broad cause groups -- 3. Leading causes of death -- 4. Cancer mortality -- 5. Causes of death among children aged under five years -- 6. Causes of death among adults aged 15-59 years -- 7. Years of life lost: taking age at death into account -- 8. Projected trends in global mortality: 2004-2030 -- Part 3: Disease incidence, prevalence and disability -- 9. How many people become sick each year? -- 10. Cancer incidence by site and region -- 11. How many people are sick at any given time? -- 12. Prevalence of moderate and severe disability -- 13. Leading causes of years lost due to disability in 2004 -- Part 4: Burden of disease: DALYs -- 14. Broad cause composition -- 15. The age distribution of burden of disease -- 16. Leading causes of burden of disease -- 17. The disease and injury burden for women -- 18. The growing burden of noncommunicable disease -- 19. The unequal burden of injury -- 20. Projected burden of disease in 2030 -- Annex A: Deaths and DALYs 2004: Annex tables -- Table A1: Deaths by cause, sex and income group in WHO regions, estimates for 2004 -- Table A2: Burden of disease in DALYs by cause, sex and income group in WHO regions, estimates for 2004 -- Table A3: Deaths by cause and broad age group, countries grouped by income per capita, 2004 -- Table A4: Burden of disease in DALYs by cause and broad age group, countries grouped by income per capita, 2004 -- Table A5: Deaths by cause, sex and age group, countries grouped by income per capita, 2004.

Table A6: Burden of disease in DALYs by cause, sex and age group, countries grouped by income per capita, 2004 -- Annex B: Data sources and methods -- B1. Population and all-cause mortality estimates for 2004 -- B2. Estimation of deaths by cause -- B3. Causes of death for children aged under five years -- B4. YLD revisions -- B5. Cause-specific revisions and updates -- B6. Prevalence of long-term disability -- B7. Projections of mortality and burden of disease -- B8. Uncertainty of estimates and projections -- Annex C: Analysis categories and mortality data sources -- Table C1: Countries grouped by WHO region and income per capita, 2004 -- Table C2: Countries grouped by income per capita, 2004 -- Table C3: GBD cause categories and ICD codes -- Table C4: Data sources and methods for estimation of mortality by cause, age and sex -- References.