Separation techniques in clinical chemistry
Title:
Separation techniques in clinical chemistry
Author:
Aboul-Enein, Hassan Y.
ISBN:
9780824755119
9780203911105
9780824740139
Publication Information:
New York : Marcel Dekker, ©2003.
Physical Description:
1 online resource (viii, 532 pages) : illustrations.
Series:
Molecular and supramolecular photochemistry ; 10
Molecular and supramolecular photochemistry ; 10.
Contents:
Preface; Contents; Contributors; Sample Pretreatment in Clinical Chemistry; Separation Science in Therapeutic Drug Monitoring; The Impact of Chirality in Pharmacokinetics and Therapeutic Drug Monitoring; HPLC in Bioavailability Examination; Validation of HPLC Analyses in Therapeutic Drug Monitoring; Analysis of Illicit Drugs with Chromatographic Methods; Biogenic Amine Neurotransmitters: Their Importance and Measurement in Human Tissue and Body Fluids; Clinical Applications of Affinity Chromatography; Immunoaffinity Chromatography in Clinical Analysis.
Electrospray Tandem Mass Spectrometry in the Biochemical Genetics LaboratoryApplication of Thin-Layer Chromatography in Clinical Chemistry; Applications of Capillary Electrophoresis in Clinical Analysis of Drugs; Index.
Abstract:
This reference examines innovations in separation science for improved sensitivity and cost-efficiency, increased speed, higher sample throughput and lower solvent consumption in the assessment, evaluation, and validation of emerging drug compounds. It investigates breakthroughs in sample pretreatment, HPLC, mass spectrometry, capillary electrophoresis and therapeutic drug monitoring for improved productivity, precision, and safety in clinical chemistry, biomedical analysis, and forensic research.From saliva, hair, and biological samples to illegal drugs and toxins, Separation Techniques i.
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