Update on Silica-based Mesoporous Materials for Biomedical Applications.
Title:
Update on Silica-based Mesoporous Materials for Biomedical Applications.
Author:
Pasqua, Luigi.
ISBN:
9781847355096
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (182 pages)
Contents:
9781847355096_Front Cover.pdf -- 9781847355096_Content.pdf -- Update on Silica-based -- Preface -- Dedication -- Acknowledgements -- Contents -- 1 Synthesis Parameters and Structural Properties of Mesoporous Silica -- 1.1 Synthesis of Mesoporous Materials -- 1.2 M41s Materials -- 1.3 MCM-41 Mesoporous Materials -- 1.4 MSU Mesoporous Materials -- 1.5 SBA Mesoporous Materials -- 2 Characterisation of Mesoporous Materials -- 2.1 Nitrogen Gas Adsorption -- 2.1.1 Classification of Pores According to their Width -- 2.2 Adsorption in Micropores -- 2.3 Adsorption in Mesopores -- 2.4 General Considerations on Adsorption -- 2.5 Adsorption in Nonporous Solids -- 2.5.1 Specific Surface Area -- 2.6 X-Ray Powder Diffraction -- 2.7 Scanning Electron Microscopy -- 2.8 Transmission Electron Microscopy -- 3 Nanostructuring Mesoporous Silica: An Overview -- 3.1 Controlling Morphology -- 3.2 Hybrid Mesoporous Silica -- 3.2.1 Post-synthesis Grafting Hybridisation -- 3.2.2 Co-condensation -- 4 Potential Applications of Mesoporous Silica -- 4.1 Potential Applications of Mesoporous Silica in -- 4.2 Potential Applications of Mesoporous Silica in -- 5 Inclusion of Biomolecules in Mesopores -- 5.1 Immobilisation of Proteins or Enzymes in -- 5.2 Mesoporous Silica in Peptide Separations for -- 5.3 Biological Molecules Included in Mesoporous -- 6 Mesoporous Silica as Matrices for Modified Drug Release -- 6.1 Generalities and Preliminary Studies for Oral Drug -- 6.2 Engineered Drug Delivery Systems -- 6.3 Drug Delivery of Anticancer Agents and -- 7 Multifunctional Mesoporous Silica in Cancer and Gene Therapy -- 7.1 Synthesising Mesoporous Materials: Towards the -- 7.2 Toxicity of Silica and Mesoporous Silica -- 7.2.1 Toxicity of Surface-functionalised and Luminescent -- 7.2.2 Studies Correlating Surface Functionalisation and -- 7.3 Engineering Drug-targeting Devices.
7.3.1 Preferential Functionalisation of External Surface of -- 7.3.2 Drug Targeting via Magnetically Active Nanoparticles -- 7.3.3 Polymeric Functionalisation of Mesoporous Silica -- 7.3.4 Mesoporous Silica Devices in Gene Transfection -- 8 Cell Markers and Bioimaging -- 9 Perspectives -- Abbreviations -- Index -- 9781847355096_Back Cover.pdf.
Abstract:
This book provides an insightful understanding of the mesoporous silica structure and its special properties. The details of synthesis and modification strategies are discussed by reviewing the open literature. The discussion concerning the potential of mesoporous silica in modern biomedical applications will be related to a critical analysis in the field of material science. This book will help the reader rapidly develop the necessary tools to follow the design of the different mesoporous silica-based devices presented in the various studies. The structure of the different devices is examined in detail and the relationship between the structure and the expected activity are discussed. It will also assist in the ability to design new therapeutic devices in a field where the applications seem to be without limits.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
Genre:
Electronic Access:
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