CONTENTS -- 1 THE PROBLEM -- An Introductory Statement -- Possible Methods of Approach -- Relevant Findings from Genetics and Other Disciplines -- A Guiding Concept of Cancer -- The Design of This Study -- A Brief Summary of Methods -- 2 THE PROPOSITAE -- Selection -- Clinical Data -- Age at First Diagnosis -- Demographic Data -- Genetic Data -- Family History of Breast Cancer -- 3 THE CONTROL GROUP -- Control Groups in Other Studies -- The Choice of a Control Group -- The Husbands' Relatives -- 4 INFORMATION ABOUT RELATIVES -- First Information -- Medical History Questionnaires -- Death Records -- Verification of Cancers -- Completeness of Reporting -- Tabulation of Data -- 5 CANCER IN RELATIVES -- Cancer Mortality -- Cancer Morbidity -- Direct Comparison between Cancer and Control Groups -- Morbid Risk -- Sequential Analysis -- The Effect of Possible Sources of Bias -- Other Findings -- 6 A SECOND SET OF PROPOSITAE -- The Propositae -- The Control Group -- Information about Relatives -- Cancer in Relatives -- 7 AN INTERPRETATION OF RESULTS -- Review of the Data -- Comparison with Other Studies -- Genetic Implications -- Clinical Implications -- Indications for Further Research -- Summary -- APPENDIXES -- A. The Propositae -- B. The Relatives -- C. Cancer Mortality -- D. Cancer Morbidity -- E. Some Forms Used in This Study -- LITERATURE CITED -- INDEX -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- L -- M -- N -- O -- P -- R -- S -- T -- U -- W.