Guide for the Care and Use of Laboratory Animals -- Copyright -- Note -- Preface -- Contents -- Introduction -- REGULATIONS, POLICIES, AND PRINCIPLES -- EVALUATION CRITERIA -- FARM ANIMALS -- NONTRADITIONAL SPECIES -- FIELD INVESTIGATIONS -- OVERVIEW -- REFERENCES -- 1 Institutional Policies and Responsibilities -- MONITORING THE CARE AND USE OF ANIMALS -- Institutional Animal Care and Use Committee -- Animal Care and Use Protocols -- Physical Restraint -- Multiple Major Surgical Procedures -- Food or Fluid Restriction -- VETERINARY CARE -- PERSONNEL QUALIFICATIONS AND TRAINING -- OCCUPATIONAL HEALTH AND SAFETY OF PERSONNEL -- Hazard Identification and Risk Assessment -- Personnel Training -- Personal Hygiene -- Facilities, Procedures, and Monitoring -- Animal Experimentation Involving Hazards -- Personal Protection -- Medical Evaluation and Preventive Medicine for Personnel -- REFERENCES -- 2 Animal Environment, Housing, and Management -- PHYSICAL ENVIRONMENT -- Microenvironment and Macroenvironment -- Housing -- Primary Enclosures -- Sheltered or Outdoor Housing -- Naturalistic Environments -- Space Recommendations -- Temperature and Humidity -- Ventilation -- Illumination -- Noise -- BEHAVIORAL MANAGEMENT -- Structural Environment -- Social Environment -- Activity -- HUSBANDRY -- Food -- Water -- Bedding -- Sanitation -- Bedding Change -- Cleaning and Disinfection of Primary Enclosures -- Cleaning and Disinfection of Secondary Enclosures -- Assessing the Effectiveness of Sanitation -- Waste Disposal -- Pest Control -- Emergency, Weekend, and Holiday Care -- POPULATION MANAGEMENT -- Identification and Records -- Genetics and Nomenclature -- REFERENCES -- 3 Veterinary Medical Care -- ANIMAL PROCUREMENT AND TRANSPORTATION -- PREVENTIVE MEDICINE -- Quarantine, Stabilization, and Separation.

Surveillance, Diagnosis, Treatment, and Control of Disease -- SURGERY -- PAIN, ANALGESIA, AND ANESTHESIA -- EUTHANASIA -- REFERENCES -- 4 Physical Plant -- FUNCTIONAL AREAS -- CONSTRUCTION GUIDELINES -- Corridors -- Animal-Room Doors -- Exterior Windows -- Floors -- Drainage -- Walls -- Ceilings -- Heating, Ventilation, and Air-Conditioning (HVAC) -- Power and Lighting -- Storage Areas -- Noise Control -- Facilities for Sanitizing Materials -- FACILITIES FOR ASEPTIC SURGERY -- REFERENCES -- APPENDIX A: Selected Bibliography -- ADMINISTRATION AND MANAGEMENT -- ALTERNATIVES -- AMPHIBIANS, REPTILES, AND FISHES -- ANESTHESIA, PAIN, AND SURGERY -- ANIMAL MODELS AND RESOURCES -- BIOHAZARDS IN ANIMAL RESEARCH -- BIRDS -- CATS AND DOGS -- DESIGN AND CONSTRUCTION OF ANIMAL FACILITIES -- ENRICHMENT -- ENVIRONMENTAL CONTAMINANTS -- ETHICS -- EUTHANASIA -- EXOTIC, WILD, AND ZOO ANIMALS -- FARM ANIMALS -- GENERAL REFERENCES -- GENETICS AND NOMENCLATURE -- LABORATORY ANIMAL CARE -- LAWS, REGULATIONS, POLICIES -- NONHUMAN PRIMATES -- NUTRITION -- OTHER ANIMALS -- PARASITOLOGY -- PATHOLOGY AND CLINICAL PATHOLOGY -- PHARMACOLOGY AND THERAPEUTICS -- RODENTS AND RABBITS -- SAMPLE SIZE AND EXPERIMENTAL DESIGN -- SERIAL PUBLICATIONS -- TECHNICAL AND PROFESSIONAL EDUCATION -- WELFARE -- APPENDIX B: Selected Organizations Related to Laboratory Animal Science -- APPENDIX C: Some Federal Laws Relevant to Animal Care and Use -- ANIMAL WELFARE -- ENDANGERED SPECIES -- APPENDIX D: Public Health Service Policy and Government Principles Regarding the Care and Use of Animals -- PUBLIC HEALTH SERVICE POLICY ON HUMANE CARE AND USE OF LABORATORY ANIMALS -- PRINCIPLES FOR THE CARE AND USE OF ANIMALS USED IN TESTING, RESEARCH, AND TRAINING -- U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training -- Index.

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