Handbook of Animal Models of Infection : Experimental Models in Antimicrobial Chemotherapy.
Title:
Handbook of Animal Models of Infection : Experimental Models in Antimicrobial Chemotherapy.
Author:
Sande, Merle A.
ISBN:
9780080533551
Personal Author:
Physical Description:
1 online resource (1169 pages)
Contents:
Front Cover -- Handbook of Animal Models of Infection -- Copyright Page -- Contents -- List of Section Editors -- List of Contributors -- Preface -- Introduction: The Role of Animal Models in the Evaluation of New Antibodies -- Section I: INTRODUCTORY BACKGROUND TO ANIMAL MODELS OF INFECTION -- Chapter 1. Early History of Animal Models of Infection -- Chapter 2. General Methodologies for Animal Models -- Chapter 3. Ethics Committees in Europe-An Overview -- Chapter 4. Animal Care and Use Committees-An American Perspective -- Chapter 5. Ethical Aspects of the Use of Animal Models of Infection -- Chapter 6. The Impact of General Laboratory Animal Health on Experimental Models in Antimicrobial Chemotherapy -- Chapter 7. Non-invasive Monitoring of Infection and Gene Expression in Living Animal Models -- Chapter 8. Considerations for Working Safely with Infectious Disease Agents in Research Agents -- Chapter 9. Analysis of Genetic Susceptibility to Infection in Mice -- Chapter 10. Formulation of Compounds and Determination of Pharmacokinetic Parameters -- Chapter 11. Methods for Obtaining Human-like Pharmacokinetic Patterns in Experimental Animals -- Chapter 12. Modes of Action of Antibiotics and Bacterial Structure: Bacterial Mass Versus their Numbers -- Chapter 13. Activity of Antibiotics Against Adherent/Slow-growing Bacteria Reflecting the Situation in vivo -- Section II: BACTERIAL INFECTION MODELS -- Chapter 14. The Mouse Peritonitis/Sepsis Model -- Chapter 15. Murine Thigh Infection Model -- Chapter 16. Mouse Subcutaneous Cotton Thread Model -- Chapter 17. Infection after Ionizing Radiation -- Chapter 18. Intra-abdominal Abscess -- Chapter 19. Mouse Peritonitis Model Using Cecal Ligation and Puncture -- Chapter 20. Murine Models of Peritonitis Involving a Foreign Body -- Chapter 21. Rat Polymicrobial Peritonitis Infection Model.
Chapter 22. Murine Thigh Suture Model -- Chapter 23. Animal Models of Melioidosis -- Chapter 24. Low Inoculum Model of Clean Wound Infection -- Chapter 25. Translocation of Gut Bacteria During Trauma -- Chapter 26. Mouse Models of Campylobacter jejuni Infection -- Chapter 27. Suckling Mouse Model of Enterotoxigenic Escherickia coli Infection -- Chapter 28. Rabbit Model of Shigellosis -- Chapter 29. RITARD Rabbit Model for Studying Vibrio cholerae and Other Enteric Infections -- Chapter 30. Mouse Model of Helicobacter priori Infection -- Chapter 31. Animal Models of Helicobacter (ferrets) -- Chapter 32. Hamster Model of Syphilis -- Chapter 33. Guinea-pig Model of Acquired and Congenital Syphilis -- Chapter 34. The Guinea-pig Model of Legionnaires Disease -- Chapter 35. Murine Models of Tuberculosis -- Chapter 36. Beige Mouse Model of Disseminated Mycobacterium avium Complex Infection -- Chapter 37. The Armadillo Leprosy Model, with Particular Reference to Lepromatous Neuritis -- Chapter 38. Models of Leprosy Infection in Mice -- Chapter 39. Hamster Model of Lyme Arthritis -- Chapter 40. Rabbit Model of Bacterial Conjunctivitis -- Chapter 41. Murine Model of Bacterial Keratitis -- Chapter 42. The Rabbit Intrastromal Injection Model of Bacterial Keratitis -- Chapter 43. Gerbil Model of Acute Otitis Media -- Chapter 44. Bacterial Otitis Externa in the Guinea-pig Model -- Chapter 45. Otitis Media: The Chinchilla Model -- Chapter 46. A Guinea Pig Model of Acute Otitis Media -- Chapter 47. Tissue Cage Infection Model -- Chapter 48. Rat Model of Bacterial Epididymitis -- Chapter 49. Mouse Model of Mycoplasma Genital Infections -- Chapter 50. Mouse Model of Ascending Urinary Tract Infection -- Chapter 51. Mouse Model of Ascending UTI Involving Short and Long-term Indwelling Catheters -- Chapter 52. Rat Bladder Infection Model.
Chapter 53. Rabbit Model of Catheter-associated Urinary Tract Infection -- Chapter 54. Subclinical Pyelonephritis in the Rat -- Chapter 55. Models of Acute and Chronic Pyelonephritis in the Rat -- Chapter 56. Rat Model of Chronic Cystitis -- Chapter 57. Mouse Pneumococcal Pneumonia Models -- Chapter 58. Animal Models of Gram-negative Bacillary Experimental Pneumonia -- Chapter 59. Models of Pneumonia in Ethanol-treated Rats -- Chapter 60. Pneumococcal Pneumonia and Bacteria in a Cirrhotic Rat Model -- Chapter 61. Rat Model of Chronic Pseudomonas aeruginosa Lung Infection -- Chapter 62. Hamster Model of Mycoplasma Pulmonary Infections -- Chapter 63. Murine Models of Pneumonia Using Aerosol Inoculation -- Chapter 64. Experimental Models of Infectious Arthritis -- Chapter 65. Experimental Group B Streptococcus Arthritis in Mice -- Chapter 66. Rat Model of Bacterial Osteomyelitis of the Tibia -- Chapter 67. Hematogenous Osteomyelitis in the Rat -- Chapter 68. Rabbit Model of Bacterial Osteomyelitis of the Tibia -- Chapter 69. Arthroplasty Model in Rats -- Chapter 70. Arthroplasty Model in Rabbits -- Chapter 71. Mouse Model of Streptococcal Fasciitis -- Chapter 72. Rabbit Model of Bacterial Endocarditis -- Chapter 73. Infant Rat Model of Acute Meningitis -- Chapter 74. Adult Rat Model of Meningitis -- Chapter 75. Rabbit Model of Bacterial Meningitis -- Chapter 76. Escherichia coli Brain Abscess Method in Rat -- Section III: MYCOTIC INFECTION MODELS -- Chapter 77. Rodent Models of Candida Sepsis -- Chapter 78. A Generalized Candida albicans Infection Model in the Rat -- Chapter 79. Experimental Oropharyngeal and Gastrointestinal Candida Infection in Mice -- Chapter 80. Paw Oedema as a Model of Localized Candidiasis -- Chapter 81. Murine Model of Allergic Bronchopulmonary Aspergillosis -- Chapter 82. Experimental Pulmonary Cryptococcal Infection in Mice.
Chapter 83. Experimental Pulmonary Cryptococcus neoformans Infection in Rats -- Chapter 84. Rat Model of Invasive Pulmonary Aspergillosis -- Chapter 85. Rabbit Model of Candida Keratomycosis -- Chapter 86. Experimental Candida Endocarditis -- Chapter 87. Rabbit Model of Cryptococcal Meningitis -- Chapter 88. Rat Models of Ascending Pyelonephritis Due to Candida albicans -- Chapter 89. Rat Model of Candida Vaginal Infection -- Chapter 90. Murine Models of Candida Vaginal Infections -- Chapter 91. Sporotrichosis -- Section IV: PARASITIC INFECTION MODELS -- Chapter 92. Malaria -- Chapter 93. Animal Models of Cutaneous Leishmaniasis -- Chapter 94. Animal Models of Visceral Leishmaniasis -- Chapter 95. Animal Models of Acute (first-stage) Sleeping Sickness -- Chapter 96. Animal Models of CNS (second-stage) Sleeping Sickness -- Chapter 97. Animal Models of Trypanosoma cruzi Infection -- Chapter 98. Animal Models of Toxoplasma Infection -- Chapter 99. Animal Models of Coccidia Infection -- Chapter 100. Animal Models of Trichomonas vaginalis Infection with Special Emphasis on the Intravaginal Mouse Model -- Chapter 101. Animal Models of Cryptosporidium Gastrointestinal Infection -- Chapter 102. Animal Models of Entamoeba histolytica Infection -- Chapter 103. Animal Models of Giardiasis -- Chapter 104. Schistosomosis -- Chapter 105. Animal Models for Echinococcosis -- Chapter 106. Intestinal Worm Infections -- Section V: VIRAL INFECTION MODELS -- Chapter 107. Animal Models for Central Nervous System and Disseminated Infections with Herpes Simplex Virus -- Chapter 108. Animal Models of Herpesvirus Genital Infection: Guinea-Pig -- Chapter 109. Animal Models of Herpes Skin Infection: Guinea-pig -- Chapter 110. Animal Models of Ocular Herpes Simplex Virus Infection (Rabbits, Primates, Mice) -- Chapter 111. Animal Models for Cytomegalovirus Infection: Murine CMV.
Chapter 112. Animal Models for Cytomegalovirus Infection: Guinea-Pig CMV -- Chapter 113. Animal Models for Cytomegalovirus Infection: Rat CMV -- Chapter 114. Human Cytomegalovirus Infection of the SCID-hu (thy/liv) Mouse -- Chapter 115. Animal Model for Ocular Human Cytomegalovirus Infections in SCID-hu Mice -- Chapter 116. Animal Models for Varicella Zoster Infections: Simian Varicella -- Chapter 117. Varicella Zoster Infection of T cells and Skin in the SCID-hu Mouse Model -- Chapter 118. The Mouse Model of Influenza Virus Infection -- Chapter 119. The Ferret as an Animal Model of Influenza Virus Infection -- Chapter 120. The Cotton Rat as a Model of Respiratory Syncytial Virus Pathogenesis, Prophylaxis and Therapy -- Chapter 121. Animal Models for Coxsackievirus Infections -- Chapter 122. Animal Models for HBV Infections-Transgenic Mice -- Chapter 123. Animal Models for Hepatitis B Infections-Duck Hepatitis -- Chapter 124. Woodchuck Model of Hepatitis B Virus Infection -- Chapter 125. Animal Models of Papillomavirus Infections -- Chapter 126. Adult Mouse Model for Rotavirus -- Chapter 127. Animal Models for Lentivirus Infections-Feline Immunodeficiency Virus -- Chapter 128. Animal Models of HIV Infection: SIV Infection of Macaques -- Chapter 129. The SCID-hu Thy-Liv Mouse: an Animal Model for HIV- 1 Infection -- Chapter 130. Animal Models for HIV Infection: hu-PBL- SCID Mice -- Chapter 131. Chimpanzee Model of HIV- 1 Infection.
Abstract:
Handbook of Animal Models of Infection is a complete revision of a three-volume text that was published in 1986. It incorporates the major advances in the field during the past decade, in particular those concerning molecular biological procedures and new models that have been developed. It focuses on both methods and techniques, which makes it an essential and comprehensive reference as well as a benchtop manual. The Handbook will help investigators save time and effort in formulating an approach to test a new potential therapeutic agent or combination of agents for in vivo efficacy and to position the therapy for specific infections where it may have therapeutic promise. The book is divided into five sections; the first covering the general methodologies, followed by sections describing experimental bacterial, mycotic, parasitic, and viral infections. Key Features * Discusses ethical and safety aspects in an introductory background section * Covers principles of animal care and current techniques appropriate for the use of animal models of infection * Details a wide range of animals including rodents, rabbits, cats, and primates * Provides hands-on descriptions of how to set up the model * Discusses the major advantages and limitations of each model * Ensures full coverage of bacterial, fungal, viral, and parasitic infections.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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