Practical Manual of Clinical Obesity -- Copyright -- Contents -- Preface -- Part I The Biology of Obesity-Why It Occurs -- Chapter 1 Energy Balance and Body Weight Homeostasis -- Introduction -- Basic concepts and principles in human energetics -- Components of energy expenditure -- Mechanisms of thermogenesis -- Inter-individual variability in metabolic adaptation -- Key web links -- Further reading -- Chapter 2 The Genetic Basis of Obesity -- Introduction -- Evidence for the heritability of fat mass -- Gene-environment interactions -- Molecular mechanisms involved in energy homeostasis -- Human monogenic obesity syndromes -- Fat mass and obesity-associated gene (FTO) -- Pleiotropic ("syndromic") obesity -- Summary -- Key web links -- Further reading -- Chapter 3 Adipocyte Biology -- Introduction -- TAG storage and release -- Secretory function of WAT -- Brown adipose tissue (BAT) -- Conclusion -- Key web links -- Further reading -- Chapter 4 Fetal and Infant Origins of Obesity -- Introduction -- Measurement -- Conceptual framework of early origins of obesity -- Modifiable developmental disease determinants -- Summary -- Key web links -- Further reading -- Chapter 5 Metabolic Fuels and Obesity -- Introduction -- Physiological conditions in weight-stable individuals -- Exercise -- Summary -- Key web links -- Further reading -- Part 2 Clinical Management of the Obese Individual -- Chapter 6 Practical Guide to Clinical Assessment and Treatment Planning -- Setting up a clinic -- Broaching the topic of obesity -- Taking an obesity-focused history -- Physical examination of the obese patient -- Identifying the high-risk obese patient -- Key web links -- Further reading -- Chapter 7 Stages of Obesity and Weight Maintenance -- Stages of obesity -- Factors affecting weight loss maintenance -- The successful weight maintainer -- Further reading.

Chapter 8 Dietary Management -- Specific strategies to help patients reduce calories -- Key web links -- Further reading -- Chapter 9 Physical Activity and Exercise -- Exercise and weight reduction -- Exercise and obesity-related CVD -- Key web links -- Reference -- Further reading -- Chapter 10 Behavior Therapy -- Principles of behavior therapy -- Components of behavioral treatment -- Key web links -- Further reading -- Chapter 11 Pharmacotherapy -- The legacy of anti-obesity medications -- Drugs that reduce food intake primarily by acting on the CNS -- Drugs that reduce fat absorption -- Weight-gaining medications -- Key web links -- Further reading -- Chapter 12 Surgery -- Weight loss procedures -- Weight loss and complications -- Effect on co-morbid conditions -- Changes in QOL after bariatric surgery -- Patient selection and pre-operative management -- Post-operative management -- Key web links -- References -- Further reading -- Part 3 Clinical Management of Obesity-Related Co-morbidities -- Chapter 13 Diabetes and Metabolic Diseases -- Principles guiding management -- Management algorithm -- Key web links -- References -- Further reading -- Chapter 14 Obesity and Reproductive Health -- Obesity and reproductive health -- Managing PCOS -- Obesity and assisted reproduction therapy (ART) -- Managing the pregnant obese woman -- Key societies -- Key web links -- Further reading -- Chapter 15 Gastro-intestinal and Hepatobiliary Disease -- Non-alcoholic fatty liver disease (NAFLD) -- Gallbladder disease -- Gastritis and GERD -- Other GI disorders -- Key web links -- Further reading -- Chapter 16 Respiratory Disease -- Obesity and lung function -- Common respiratory diseases associated with obesity -- Obstructive sleep apnea (OSA) -- Obesity hypoventilation syndrome (OHS) -- Management algorithm for OSA -- Key web links -- Further reading.

Chapter 17 Obesity and Cardiovascular Disease -- Introduction -- Obesity and CVD risk -- Physical fitness and cardiovascular risk in obesity -- Obesity and hypertension -- Obesity and stroke -- Obesity and CHF -- Obesity and sudden death -- Management of cardiovascular risk in obesity -- Key web links -- Reference -- Further reading -- Chapter 18 Obesity: Mental Health and Social Consequences -- Principles for management -- Obesity and mental illness -- Obesity and major psychiatric diseases -- Obesity and mental well-being in children -- Management -- Key web link -- Further reading -- Chapter 19 Obesity and Musculo-skeletal Disease -- Obesity and musculo-skeletal disease -- Obesity and osteoarthritis -- Obesity and gout -- Obesity and low back pain -- Management algorithms -- Key web link -- Further reading -- Chapter 20 The Obese Patient in Hospital -- Specialist equipment for the morbidly obese -- Emergency care -- Managing the severely obese in hospital -- Key web links -- Further reading -- Conversion Table -- Index.