A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
Title:
A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
Author:
Gibbs, Elizabeth M.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (354 seconds)
Series:
Behavior
General Note:
Title from resource description page
Abstract:
This protocol describes a flexible, low-cost system for measuring mouse ambulation in an open field activity assay. We show that a 6-minute ambulation assay based on this system detects a decrease in voluntary movement in mdx mice, and accurately distinguishes improvement in a muscle-specific rescue of these animals.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/56772