Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
Title:
Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
Author:
Bender, Heather R.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (633 seconds)
Series:
Bioengineering
General Note:
Title from resource description page
Abstract:
The goal of this protocol is to use cationic/anionic liposomes with a neuro-targeting peptide as a CNS delivery system to enable siRNA to cross the BBB. The optimization of a delivery system for treatments, like siRNA, would allow for more treatment options for prion and other neurodegenerative diseases.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/54106