Systems biology properties of reconstructed networks
Title:
Systems biology properties of reconstructed networks
Author:
Palsson, Bernhard.
ISBN:
9780521859035
9780511145124
9781601197603
9780511790515
Personal Author:
Publication Information:
Cambridge ; New York : Cambridge University Press, 2006.
Physical Description:
1 online resource (xii, 322 p.) : ill.
Contents:
Introduction -- Basic concepts in systems biology -- Metabolic networks -- Transcriptional regulatory networks -- Signaling networks -- Basic features of the stoichiometric matrix -- Topological properties -- Fundamental subspaces of S -- The (right) null space of S -- The left null space of S -- The row and column spaces of S -- Dual causality -- Properties of solution spaces -- Sampling solution spaces -- Finding functional states -- Parametric sensitivity -- Epilogue.
Abstract:
The new discipline of sytems biology examines how genome sequences interact and form networks. This text describes how to model networks, how to determine their properties, and how to relate these to phenotypic functions. The prerequisites for this text are knowledge of linear algebra and biochemistry.
Genre:
Electronic Access:
Knovel http://app.knovel.com/web/toc.v/cid:kpSBPRN005