Frontmatter -- Acknowledgments -- Contents -- Summary -- Introduction -- 1 Security Context for the Biological Threat Reduction Program -- 2 Achievements of the Biological Threat Reduction Program -- 3 U.S. Government-Wide Biological Threat Reduction Programs and Interagency Coordination -- 4 Overcoming Obstacles Confronting the Biological Threat Reduction Program -- 5 Future of the Biological Threat Reduction Program -- 6 Recommendations -- Appendix A National Research Council Committee on Prevention of Proliferation of Biological Weapons -- Appendix B Extracts from Recent National Research Council Reports -- Appendix C Relevant Reports by the National Academies -- Appendix D Relevant Recent Reports by the U.S. Government Accountability Office -- Appendix E Other Reports of Interest -- Appendix F Research Projects Supported under the Cooperative Biological Research Program (1999-present) -- Appendix G Agenda -- Appendix H Foreign Colleagues Who Participated in Discussions of BTRP in Garmisch, Germany (April 2007).