Examining BCL-2 Family Function with Large Unilamellar Vesicles
Title:
Examining BCL-2 Family Function with Large Unilamellar Vesicles
Author:
Asciolla, James J.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (515 seconds)
Series:
Biology
General Note:
Title from resource description page
Abstract:
Biochemically-defined large unilamellar vesicles (LUVs) are a convenient model system to analyze BCL-2 family interactions with immediate implications in better understanding the mitochondrial pathway of apoptosis. A method to produce LUVs, along with standard BCL-2 family protein combinations and controls to examine LUV permeabilization, are presented.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/4291