ADVANCES IN MEDICINE AND BIOLOGY. VOLUME 14 -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I: Methods of Study of Energy Expenditure -- Abstract -- Introduction -- Methods of Study of Energy Expediture -- Indirect Calorimetry -- Direct Calorimetry -- Doubly-Labeled Water Method -- Energy Balance Studies -- Movement Sensors -- Heart Rate Monitoring -- Core Body Temperature -- Heat Flow Measurement -- Combined Methods -- References -- Chapter II: Pompe Disease: Symptoms, Diagnosis and Treatment -- Abstract -- Introduction -- Clinical Presentation -- Infantile onset of Disease -- Childhood or Juvenile or Adult form of Disease (Late onset or Non Classic form of the Disease) -- Diagnosis -- Blood Chemistry Study -- Electromyography and Electrocardiography -- Muscle Biopsy -- Measurement of Enzyme Activity -- Mutation Study -- Prenatal Diagnosis -- Therapeutic Approaches -- Effect of ERT in Infantile Pompe Disease -- Effect of ERT in Late onset Pompe Disease -- Safety and Limitations of ERT -- Future Perspectives and Experimental Therapies -- Conclusion -- Acknowledgments -- References -- Chapter III: Review Insulin Resistance: Intra-Uterine Growth Retardation, Life Style, Genetic Susceptibility, Prevention and Treatment -- Abstract -- Metabolic Syndrome -- 1. Intra-Uterine: Growth Retardation, Epigenesis -- 2. Life Style: Obesity, Sexe Differences, Race, Physical Activity and Psychosocial Stress -- 3. Genetic Susceptibility: "Thrifty Genesand Inflammation" -- 4. Prevention and Treatment -- References -- Chapter IV: Microbial Diversity of Biofilm Technologies used for Water Treatment -- Abstract -- Introduction -- Microbial Diversity Methodology -- Biofilm Diversity in Submerged Biofilter Technologies for Water Treatment -- Current Problems and Future Trends in Microbial Population Assessment -- References.

Chapter V: Applying Project Management to Evidence-Based Medicine Research -- Abstract -- Introduction -- Medical Research -- Project Management Applied to EBM -- Discussion -- References -- Chapter VI: Genetic Counseling for Pompe Disease -- Abstract -- Introduction -- Confirming a Diagnosis -- Education and Psychosocial Counseling for Pompe Disease -- Treatment and Management Options -- Assessing Disease Progression -- Managing Disease Progression and Follow up -- Conclusion -- Reviewed by -- Supported by -- References -- Chapter VII: Therapeutic Values of Vitamin E Supplements in Clinical Practices -- Abstract -- Background -- Chemistry -- Vitamin E Supplement -- Clinical Indications -- Other Applications -- Clinical Pharmacology -- Dosage -- Metabolism and Mechanisms -- Clinical Trials -- Conclusion -- References -- Chapter VIII: The Influence of the Nutrient Load on the Formation of Escherichia Coli Biofilms -- Abstract -- 1. Introduction -- 2. Experiental Set-up -- 3. Results and Discussion -- Acknowledgments -- References -- Chapter IX: Physiology and Pathophysiology of Megalin-Mediated Endocytosis in Renal Proximal Tubule Cells -- Abstract -- Introduction -- Megalin, a Major Endocytic Receptor in PTC -- Molecules Associated with Megalin's Functions in PTC -- Regulation of Megalin Expression -- Intracellular Adaptor Proteins and Motors that Interact with Megalin -- Handling of Albumin in PTC, Related to Mechanisms of Albuminuria -- Overloaded Endocytosis-Induced PTC Injury -- Megalin-Mediated Signal Transduction -- Clinical Application of Detection of Megalin Shed in Urine -- Conclusion -- Acknowledgments -- References -- Chapter X: In Vitro Expanded CD8+ NKT-Like Cells Possess Potent Cytotoxic and Immunosuppressive Activities -- Abstract -- Abbreviations -- Introduction -- Materials and Methods -- In Vitro Suppression Assays.

RT-PCR Analysis -- Results -- Suppressive Activity of CD8+ NKT-Like Cells is Mostly Cell Contact-Dependent -- Discussion -- Acknowledgment -- References -- Chapter XI: Severe Late Onset Pompe Disease: Management and Treatments -- Abstract -- Introduction -- Respiratory Management -- Respiratory and Sleep Exploration -- Prevalence of Patients Needing Invasive or Non-Invasive Ventilation -- Relationship between Respiratory Impairment and Muscular Impairment -- Effect of Enzymotherapy -- Conclusion -- References -- Chapter XII: Biofilm Development Kinetics -- Abstract -- 1. Introduction -- 2. Growth Kinetics of Microorganisms and Biofilm -- 3. Population of Microorganisms -- 4. Structure of Biofilm -- 5. Case Studies -- Conclusion -- Appendix A: Integral of Equation -- Appendix B: Properties of Coefficient P -- References -- Chapter XIII: Definition of Empirical Physical Parameter of Food Texture for Infants and that for Dysphagic Patients and People Having Difficulty in Swallowing Using Official Puncture Tests in Japan -- Abstract -- Introduction -- Materials and Methods -- Conclusion -- Nomenclature -- References -- Index.