A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Title:
A Two-Step Protocol for Umpolung Functionalization of Ketones Via Enolonium Species
Author:
Arava, Shlomy
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (492 seconds)
Series:
Chemistry
General Note:
Title from resource description page
Abstract:
A two step one-pot protocol for the umpolung of ketone enolates to enolonium species and addition of a nucleophile to the α-position is described. Nucleophiles include chloride, azide, azoles, allyl-silanes, and aromatic compounds.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/57916