Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Title:
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Author:
Feng, Pengju
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (523 seconds)
Series:
Chemistry
General Note:
Title from resource description page
Abstract:
An operationally simple procedure for the synthesis of ortho-trifluoromethoxylated aniline derivatives via a two-step sequence of O-trifluoromethylation of N-aryl-N-hydroxyacetamide followed by thermally induced intramolecular OCF3-migration is reported.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/53789