Title Page -- Copyright -- Dedication -- Mathematical symbols (with normal units) -- Greek -- Latin -- Acronyms and abbreviations -- Preface -- Acknowledgements -- About the companion website -- Part I: Product considerations: medicinal formulations -- Chapter 1: Historical perspective -- 1.1 Landmarks -- 1.2 Significant discoveries -- 1.3 Difficulties -- 1.4 Traditional uses -- 1.5 Product regulation -- Chapter 2: What is an emulsion? -- 2.1 States of matter -- 2.2 Summary thermodynamics -- 2.3 Interfacial tension and wetting -- 2.4 Shear and size reduction -- 2.5 Raw materials -- Chapter 3: Stability, metastability and instability -- 3.1 Stokes' law -- 3.2 Derjaguin-Landau-Verwey-Overbeek (DLVO) theory -- 3.3 Interfacial rheology -- Chapter 4: Manufacture -- 4.1 Premixing -- 4.2 High-shear mixers and size reduction -- 4.3 Multiple and microemulsions -- 4.4 Hot melt (steriles) -- 4.5 Filling -- Part II: Forms, uses and applications: biopharmaceutics -- Chapter 5: Creams and ointments -- 5.1 Nutraceuticals and cosmeceuticals -- 5.2 Medicinals -- Chapter 6: Pastes and bases -- 6.1 Emolliency -- 6.2 Suppositories -- 6.3 Pessaries -- Chapter 7: IV colloids -- 7.1 Needle free -- 7.2 Ocular therapy -- 7.3 Cancer -- 7.4 Antimicrobials -- 7.5 Temperature-sensitive matrices and release forms -- 7.6 Targeted endosomal use -- 7.7 Solid lipid nanoparticles -- 7.8 Diagnostic emulsions -- Chapter 8: Transdermal patches: semisolids -- 8.1 Hormones -- 8.2 Analgesia -- 8.3 Anaesthesia -- 8.4 Nicotine -- 8.5 Inserts: vaginal rings -- Chapter 9: Gels -- 9.1 Micro- and nanogels -- 9.2 Semisolids -- Chapter 10: Implants -- 10.1 Plastics and glasses -- 10.2 Thermoresponsive materials -- Chapter 11: De novo science, sustainable novel products and platform applications -- 11.1 Tablets -- 11.2 Metered-dose inhalers -- 11.3 Blood substitutes.

Part III: Tests: chemistry to control the quality, efficacy and fitness for purpose of a product -- Chapter 12: Physicochemical properties -- 12.1 Thermal evaluation (differential scanning calorimetry) and lipid polymorphs -- 12.2 Drug form, log P and Lipinski rules -- 12.3 Skin and epithelial models -- 12.4 Drug delivery routes -- Chapter 13: Sizing and microscopy -- 13.1 potential -- 13.2 Hydrodynamic diameter -- Chapter 14: Rheology, texture, consistency and spreadability -- 14.1 Bulk properties -- 14.2 Solid-state and nanorheological properties -- 14.3 Interfacial properties -- Chapter 15: Quality control, process analytical technology and accelerated testing -- 15.1 Preformulation, high-throughput screening -- 15.2 Industrial concerns -- 15.3 Rancimat and other methods -- Questions -- Guide for readers -- Specimen 'test' questions -- Answers -- References -- Index.