Cover -- Title Page -- Copyright -- Contents -- List of Contributors -- Preface -- Chapter 1 Cosmeceuticals and Clinical Practice -- Definition and regulatory issues -- The cosmeceutical marketplace -- Cosmeceuticals in cosmetic practice -- Skin care regimens based on science -- Office dispensing -- Efficacy and safety -- Conclusion -- Further reading -- Part I Development, Formulation and Evaluation of Cosmeceuticals -- Chapter 2 Bench to Beauty Counter: Development of Cosmeceuticals -- Introduction -- Foundation for the development process -- The science of formulation chemistry: product prototypes development -- Toxicology, safety and stability evaluation -- Conclusion -- Further reading -- Chapter 3 Evaluating Cosmeceuticals -- Introduction -- In vitro evaluations -- In vivo evaluations -- Conclusion -- Further reading -- Chapter 4 Modalities for Increasing Penetration -- Introduction -- Emulsions -- Barrier degradation -- Liposomes -- Nanotechnology penetration enhancement -- Penetration-enhancing devices -- Conclusion -- Further reading -- Chapter 5 Nanopharmaceuticals and Nanocosmeceuticals -- Introduction -- Nanotechnology in dermatology -- Nanovehicles -- Nanoparticle modification and functionalization -- Nanoparticles in dermatology -- Regulation and safety -- Conclusion -- Further reading -- Chapter 6 Cutaneous Barrier Function, Moisturizer Effects and Formulation -- Barrier function -- Stratum corneum structure and function -- Desquamation -- Exogenous conditions effect barrier function -- Water and its effect on the epidermis -- Moisturizing basics -- Emulsions -- Contents of a moisturizer -- Choosing a moisturizer -- Conclusion -- Further reading -- Part II Cosmeceutical Ingredients.

Chapter 7 Cosmeceutical Uses and Benefits of Alpha, Poly and Bionic Hydroxy Acids -- Introduction -- Hydroxyacid classification: AHA, PHA, BA -- Benefits of hydroxyacids by skin condition -- Formulating with AHAs -- Conclusion -- Further reading -- Chapter 8 Vitamin A: Retinoids and the Treatment of Aging Skin -- Introduction -- Define the active ingredient -- The biology of aging skin -- Mechanisms of action -- Clinical benefits -- Indications and contraindications -- Side effects -- Conclusion -- Further reading -- Chapter 9 Vitamin C Cosmeceuticals -- Introduction -- Vitamin C: stability and derivatives -- Vitamin C: an important antioxidant -- Vitamin C and photoprotection -- Vitamin C, collagen synthesis and wrinkles -- Clinical studies: treating photoaging -- Vitamin C: an important skin lightener -- Vitamin C: A potent anti-inflammatory -- Conclusion -- Further reading -- Chapter 10 Niacinamide: A Topical Vitamin with Wide-Ranging Skin Appearance~Benefits -- Introduction -- Active ingredient -- Mechanisms of action -- Clinical benefits -- Uses -- Possible side effects -- Conclusion -- Further reading -- Chapter 11 Innovative Botanicals -- Introduction -- Pine bark extract (PBE) -- Coffea arabica -- Pomegranate -- Tea tree oil -- Grape seed extract -- Conclusion -- Further reading -- Chapter 12 Green Tea Extract -- Introduction -- Active ingredient -- Mechanisms of action -- Clinical benefits -- Treatment of warts -- Chemoprevention -- Possible side effects -- Contraindications -- Conclusion -- Further reading -- Chapter 13 Soy and Oatmeal-Based Cosmeceuticals -- Introduction -- Colloidal oatmeal -- Soy -- Conclusion -- Further reading -- Chapter 14 Bioactive Peptides -- Introduction -- Definition of peptide -- Role of peptides in skin -- The development of peptide actives -- Clinical benefits -- Conclusion -- The future -- Further reading.

Chapter 15 Growth Factors in Cosmeceuticals -- Introduction -- Pathophysiology of skin aging -- Comparison of skin aging with wound formation and healing -- Growth factors and cytokines in skin aging -- Clinical benefits and indications -- New developments -- Safety and efficacy considerations -- Conclusion -- Further reading -- Chapter 16 Resveratrol and Synthetic Sirtuin Activators -- Introduction -- Resveratrol: a sirtuin activator -- Resveratrol: photoprotection and chemoprevention -- Resveratrol as an anti-aging agent -- Resveratrol as a phytoestrogen -- Delivery of resveratrol -- Synthetic sirtuin activators (STACs) -- Sirtuins, resveratrol and STACs: the controversy -- Yeast biopeptides as sirtuin activators -- Conclusion -- Further reading -- Chapter 17 Skin Aging, Glycation and Glycation Inhibitors -- Introduction -- Sugar and advanced glycation end products -- Glycation and aging skin -- Glycation inhibitors -- Cosmeceutical ingredients -- Herbs and spices -- Glycation inhibitors from marine sources -- Other important glycation inhibitors -- Conclusion -- Further reading -- Chapter 18 Essential Ions and Bioelectricity in Skin Care -- Ion flow and bioelectricity -- Essential mineral ions and skin -- Further reading -- Chapter 19 Stem Cell Cosmeceuticals -- Strategies to energize cells to rejuvenate skin -- Conclusion -- Further reading -- Chapter 20 Cosmeceutical Applications from Marine Organisms -- Introduction -- Marine-derived compounds from marine organisms -- Cosmeceutical potential of marine organism -- Conclusion -- Further reading -- Part III Practical Applications for Cosmeceuticals -- Chapter 21 Cosmeceuticals for the Treatment of Acne Vulgaris -- Introduction -- Clinical description: acne vulgaris -- The role of cosmeceuticals in treating acne -- Conclusion -- Further reading.

Chapter 22 Cosmeceutical Skin Lighteners -- Introduction -- The melanin production pathway -- Skin-lightening agents -- Cosmeceutical Ingredients for Skin Lightening -- Conclusion -- Further reading -- Chapter 23 Cosmeceuticals for Treating Cellulite -- Introduction -- Clinical description of the challenge (disease pathogenesis and challenges in treatment) -- The role of cosmeceuticals in treating this condition -- Cosmeceutical ingredients and actives appropriate for treating this condition -- Adverse effects -- Conclusion -- Further reading -- Chapter 24 Cosmeceuticals for Hair Loss and Hair Care -- Introduction -- Polyphenols: grape seed, apple extract, barley, and raspberry -- Isoflavones and soy -- Ginseng, gingko and relatives -- Plant-derived 5-alpha-reductase inhibitors -- Essential oils -- Vitamin C -- Amino acids and their derivatives -- Products for hair coloring -- Products for hair care and hair protection -- Cassia plant -- Honeydew -- Eucalyptus -- Conclusion -- Further reading -- Chapter 25 Cosmeceuticals for Treating and Preventing Scars -- Introduction -- Pathogenesis -- Risk factors -- Cosmeceutical actives that are most commonly used in the prevention and treatment of scars -- Natural therapies -- Conclusion -- Further reading -- Chapter 26 Sun Protection and Self-Tanners -- Introduction -- Spectral differences related to UV photocarcinogenesis -- Topical photoprotection -- Sunscreening agents and mechanisms of action -- Effectiveness of photoprotection -- Sunless tanning -- Future outlook -- Further reading -- Chapter 27 Cosmeceuticals for Rosacea and Facial Redness -- Introduction -- Biochemical pathways -- Basic skin care needs for rosacea management -- Role of cosmeceuticals in managing rosacea -- Advances in cosmetic actives -- Conclusion -- Further reading.

Chapter 28 Cosmeceuticals for Enhancing Cosmetic Procedures -- Introduction -- General considerations -- Synergistically enhancing procedural outcomes -- Minimizing procedural complications -- Conclusion -- Further reading -- Chapter 29 The Future of Cosmeceuticals -- Introduction -- Challenges for the Future -- Sustainable practices -- Beyond cosmeceuticals: nutraceuticals -- Conclusion -- Further reading -- Index.