Cover image for Population Biology and Criticality : From Critical Birth-Death Processes to Self-Organized Criticality in Mutation Pathogen Systems.
Population Biology and Criticality : From Critical Birth-Death Processes to Self-Organized Criticality in Mutation Pathogen Systems.
Title:
Population Biology and Criticality : From Critical Birth-Death Processes to Self-Organized Criticality in Mutation Pathogen Systems.
Author:
Stollenwerk, Nico.
ISBN:
9781848164024
Personal Author:
Physical Description:
1 online resource (250 pages)
Contents:
Contents -- Preface -- Chapter 1 From Deterministic to Stochastic Dynamics -- 1.1 Basic Probability Theory: The Tool Box -- 1.2 Stochastic Description of a Deterministic System: The Ulam Map -- 1.3 A Fully Stochastic Dynamic System: The AR(1)-Process -- 1.4 From Perron-Frobenius to Master Equation -- 1.5 A First Example of a Master Equation: The Linear Infection Model -- 1.5.1 Solving the first example of a master equation -- 1.5.2 Solution of the linear infection model -- 1.5.3 Mean value and its dynamics -- 1.5.4 Mean dynamics -- 1.6 The Birth and Death Process, a Non-Linear Stochastic System -- 1.7 Solution of the Birth-Death ODE Shows Criticality -- 1.7.1 Numerical integration shows power law at criticality -- 1.7.2 Temporal correlation length diverges at criticality -- Chapter 2 Spatial Stochastic Birth-Death Process or SIS-Epidemics -- 2.1 The Spatial Master Equation -- 2.1.1 A first inspection of the spatial birth-death process -- 2.2 Clusters and their Dynamics -- 2.2.1 Time evolution of marginals and local expectations -- 2.3 Moment Equations -- 2.3.1 Mean field behavior -- 2.3.2 Pair approximation -- 2.4 The SIS Dynamics under Pair Approximation -- 2.5 Conclusions and Further Reading -- Chapter 3 Criticality in Equilibrium Systems -- 3.1 The Glauber Model: Stochastic Dynamics for the Ising Model -- 3.1.1 A first glance at the dynamic Ising model -- 3.2 The Ising Model, a Paradigm for Equilibrium Phase Transitions -- 3.2.1 Distribution of magnetization and Gibbs free energy -- 3.3 Equilibrium Distribution around Criticality -- 3.3.1 Distribution of magnetization -- 3.3.2 External magnetic field -- 3.3.3 The maximum of the total magnetization distribution -- 3.3.3.1 Approximation with Lagrange polynomials -- 3.3.3.2 The maximum magnetization with changing parameters -- 3.4 Mean Field Theory and its Exponents.

3.4.1 Mean field self-consistency equation -- 3.4.2 Mean field quantities obtained from the self-consistency equation -- 3.4.2.1 Critical coupling strength in mean field approximation -- 3.4.2.2 The first critical exponent in mean field approximation -- 3.4.3 Universal scaling function and exponent δ in mean field -- 3.4.4 The magnetic susceptibility or second moment of the magnetization diverges -- 3.4.5 State equation in mean field -- 3.5 Critical Exponents of the Ising Model beyond Mean Field -- Chapter 4 Partial Immunization Models -- 4.1 A Model with Partial Immunization: SIRI -- 4.2 Local Quantities -- 4.3 Dynamics Equations for Global Pairs -- 4.3.1 The SIRI dynamics under pair approximation -- 4.3.2 Balance equations for means and pairs -- 4.4 Mean Field Model: SIRI with Reintroduced Susceptibles -- 4.4.1 Pair dynamics for the SIRI model -- 4.5 Fruitful Transfer between Equilibrium and Non-Equilibrium Systems -- Chapter 5 Renormalization and Series Expansion: Techniques to Study Criticality -- 5.1 Introduction -- 5.2 Real Space Renormalization in One-Dimensional Lattice Gas -- 5.3 Directed Percolation and Path Integrals -- 5.3.1 Master equation of the birth-death process -- 5.3.2 Schrödinger-like equation -- 5.3.3 δ-Bosons for hard-core particles -- 5.3.4 Path integral for hard-core particles in a birth-death process -- 5.4 Series Expansions -- 5.4.1 The SIS epidemic model revisited -- 5.4.2 Perturbation analysis gives critical threshold -- 5.5 Generalization to the SIRI Epidemic Model -- 5.5.1 The SIRI epidemic model -- 5.5.2 Transitions in the SIRI model -- Chapter 6 Criticality in Measles under Vaccination -- 6.1 Measles around Criticality -- 6.2 The SIR Model -- 6.2.1 The SIR model with vaccination -- 6.2.2 Stationary states and vaccination threshold -- 6.2.3 Definition and expression for the reproduction number R.

6.2.4 Vaccination level at criticality vc -- 6.2.5 Realistic parameters for measles epidemics -- 6.3 Stochastic Simulations -- 6.3.1 Stochastic bifurcation diagram for vaccine uptake -- 6.3.2 Large outbreaks during decreasing vaccine uptake -- Chapter 7 Genetics and Criticality -- 7.1 Introduction -- 7.2 Models in Genetics -- 7.2.1 The Moran model -- 7.2.2 The probability of fixation -- 7.3 Mean Time until Fixation -- Chapter 8 Evolution to Criticality in Meningococcal Disease -- 8.1 Accidental Pathogens -- 8.2 Modeling Infection with Accidental Pathogens -- 8.2.1 The meningitis model: SIRYX -- 8.2.2 The invasion dynamics of mutant strains -- 8.2.3 Divergent fluctuations for vanishing pathogenicity -- 8.3 Evolution toward Criticality -- 8.3.1 Fast and slow time scales in the meningitis model -- 8.3.2 Analytics for evolution toward criticality -- 8.3.3 Simulation for evolution toward criticality -- 8.3.4 Spatial modeling: Outbreak clusters without direct disease contacts -- 8.3.5 Mean pathogenicity goes toward zero -- 8.4 Empirical Data Show Fast Epidemic Response and Long-Lasting Fluctuations -- 8.4.1 Modeling fast epidemic response finds long-lasting fluctuations -- 8.4.2 Data with fast epidemic response and long-lasting fluctuations -- Appendix A Invariant Density of the Ulam Map -- A.1 Time Evolution Equation of the Density -- A.2 Conjugation of Ulam Map and Tent Map -- A.3 Exponential Divergence in the Ulam Map -- Appendix B Parameter Estimation for the Autoregressive AR(1)-Process Gives Least Squares Estimators -- B.1 Likelihood and its Maximization -- B.2 Bayesian Parameter Estimation -- B.2.1 Conditional posteriors -- B.2.2 Gibbs sampler -- Appendix C From Stochastic Epidemics to Parameter Estimation -- C.1 Likelihood for Simple Stochastic Epidemic Model -- C.2 Calculation of the Likelihood Function.

C.3 Confidence Intervals via Inverse Fisher Matrix -- C.4 Improving Confidence Intervals -- Appendix D Product Space for Spin 1/2 Many-Particle Systems -- Appendix E Path Integral Using Coherent States for Hard-Core Bosons -- Appendix F Analytical Power Laws in the Meningitis Model -- F.1 Distribution of Total Number of Cases -- F.2 Scaling -- F.3 Solution of Size Distribution of the Epidemic -- F.4 Size Distribution of the Epidemic for Є Zero -- Bibliography -- Index.
Abstract:
The present book describes novel theories of mutation pathogen systems showing critical fluctuations, as a paradigmatic example of an application of the mathematics of critical phenomena to the life sciences. It will enable the reader to understand the implications and future impact of these findings, yet at same time allow him to actively follow the mathematical tools and scientific origins of critical phenomena. This book also seeks to pave the way to further fruitful applications of the mathematics of critical phenomena in other fields of the life sciences.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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