Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing
Title:
Shifting Zebrafish Lethal Skeletal Mutant Penetrance by Progeny Testing
Author:
Brooks, Elliott P.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (519 seconds)
Series:
Developmental Biology
General Note:
Title from resource description page
Abstract:
The goal of this protocol is to alter the penetrance of lethal skeletal mutant phenotypes in zebrafish by selective breeding. Lethal mutants cannot be grown to adulthood and bred themselves, therefore this protocol describes a method for tracking and selecting penetrance through multiple generations by progeny testing.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/56200