Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
Title:
Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
Author:
Gabriel, Elke
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (460 seconds)
Series:
Developmental Biology
General Note:
Title from resource description page
Abstract:
Modeling human brain development has been hindered due to the unprecedented complexity of neural epithelial tissue. Here, a method for the robust generation of brain organoids to delineate early events of human brain development and to model microcephaly in vitro is described.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/55372