PARVOVIRUS B19 AND HEMATOLOGICAL DISORDERS IN CHILDREN -- CONTENTS -- PREFACE -- PARVOVIRUS B19 (PB19) -- ABSTRACT -- INTRODUCTION -- PARVOVIRUS FAMILY (PARVOVIRIDAE) -- PARVOVIRUS GENETIC STRUCTURE -- EPIDEMIOLOGY OF PB19 -- TRANSMISSION OF PB19 -- PATHOGENESIS OF PB19 INFECTION -- IMMUNE RESPONSE TO PB19 -- CONCLUSION -- REFERENCES -- CLINICAL ASPECTS OF PB19 INFECTION IN IMMUNOCOMPETENT PATIENTS -- ABSTRACT -- INTRODUCTION -- ASYMPTOMATIC INFECTION -- ERYTHEMA INFECTIOSUM (FIFTH DISEASE) -- Differential Diagnosis of Erythema Infectiosum -- GLOVES AND SOCKS SYNDROME -- ARTHROPATHY -- HYDROPS FETALIS AND STILLBIRTH -- MENINGITIS AND NEUROLOGICAL DISEASE -- MYOCARDITIS -- HEPATITIS & VASCULITIS -- SYSTEMIC SCLEROSIS -- CHRONIC FATIGUE SYNDROME -- UVEITIS -- MYOSITIS -- B) Hematological Consequences of PB19 Infection in Susceptible Patients[2] -- PREVENTION OF PB19 INFECTION -- TREATMENT AND CONTROL OF PB19 INFECTION -- CONCLUSION -- REFERENCES -- PB19 INFECTION IN IMMUNODEFICIENCY DISORDERS -- ABSTRACT -- INTRODUCTION -- IMMUNODEFICIENT PATIENTS -- Congenital Immunodeficiency Syndrome -- ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) -- Immunocompromised Patients -- PB19 Infection in Transplantation -- PB19 Infection in Patients Receiving Chemotherapy -- CONCLUSION -- REFERENCES -- HEMATOLOGICAL CONSEQUENCES OF PB19 INFECTION -- ABSTRACT -- INTRODUCTION -- PATHOGENESIS OF PB19 RELATED TO HEMATOLOGICAL DISORDERS -- Transient Aplastic Crisis (TAC) -- Idiopathic Thrombocytopenic Purpura (ITP) -- Neutropenia -- Congenital Anaemia -- Haemophagocytic Syndrome -- Chronic Bone Marrow Failure due to Persistent PB19 Infection -- Role of PB19 in Acute Leukemia (AL) -- CONCLUSION -- REFERENCES -- PB19 AND BLOOD TRANSFUSION -- INTRODUCTION -- TRANSMISSION OF PB19 BY BLOOD TRANSFUSION -- TRANSMISSION OF PB19 BY PLASMA DERIVATIVES.

LABORATORY SCREENING OF BLOOD AND BLOOD PRODUCTS -- CONTROL OF VIRAL IN BLOOD PRODUCTS -- CONCLUSION -- REFERENCES -- OCCUPATIONAL INFECTION BY PB19 -- ABSTRACT -- INTRODUCTION -- RISK OF PB19 INFECTION IN HEALTH CARE WORKERS -- RISK OF PB19 INFECTIONIN SCHOOL EMPLOYEE -- INFECTION CONTROL MEASURES FOR OCCUPATIONAL INFECTION WITH PB19 -- 1. Hospital Care Workers -- 2. School Employee -- CONCLUSION -- REFERENCES -- PB19 GENETIC STUDY, RELATION TO PATHOGENESIS -- ABSTRACT -- INTRODUCTION -- PROMOTER REGION -- NS REGION -- 4.4. VP REGION -- VARIANT GENOTYPES OF PARVOVIRUS B19 -- CONCLUSION -- REFERENCES -- LABORATORY DIAGNOSIS OF PB19 -- ABSTRACT -- INTRODUCTION -- DIAGNOSIS OF PB19 INFECTION -- 1) Diagnostic Cytopathology -- 3) Detection of Specific Antibodies to PB19 StructuralProteins VP1, VP2 & Non-Structural Protein NS1 -- 1) Diagnostic Cytopathology (Figure 5) -- 2) Direct Detection of the Virus by -- a) Electron Microscope (EM) -- b) Culture of PB19 -- c) Detection of PB19 Antigens in the Serum -- D) Immunohistochemical Detection of PB19Antigen in Formalin-Fixed -- E) Detection of Viral DNA -- 3) Detection of Specific Antibodies to PB19 Structural Proteins VP1, VP2 and Non-Structural Protein NS1 -- CONCLUSION -- REFERENCES -- INDEX.