Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Title:
Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations
Author:
Arimilli, Subhashini
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (565 seconds)
Series:
Immunology and Infection
General Note:
Title from resource description page
Abstract:
Using optimized human peripheral blood mononuclear cell (PBMC) ex vivo assays, we showed that a combustible tobacco product preparation markedly suppresses receptor-mediated intracellularly secreted cytokines and cytolytic ability of effector PBMCs. These rapid assays may be useful in product evaluation and understanding the potential long-term effects of tobacco exposure.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/52351