Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
Title:
Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
Author:
Chen, Elijah W.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (529 seconds)
Series:
Immunology and Infection
General Note:
Title from resource description page
Abstract:
This paper uses a flow-cytometry-based assay to screen libraries of chemical inhibitors for the identification of inhibitors and their targets that influence T-cell receptor signaling. The methods described here can also be expanded for high-throughput screenings.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/58946