Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain
Title:
Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain
Author:
Bhattarai, Prabesh
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (601 seconds)
Series:
Neuroscience
General Note:
Title from resource description page
Abstract:
This protocol describes the synthesis, characterization, and injection of monomeric amyloid-β42 peptides for generating amyloid toxicity in adult zebrafish to establish an Alzheimer's disease model, followed by histological analyses and detection of aggregations.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/56014