PREFACE -- WELCOME -- ANATOMY AND PHYSIOLOGY Louis Pasquale, Jost Jonas, Douglas Anderson -- Anatomy of blood from the heart to the eye -- Blood supply of the optic nerve -- Overview of blood flow regulation in general -- The mediators of autoregulation -- The anatomic underpinning of ocular blood flow control -- The ocular vasculature and its role in regulating blood flow to the optic nerve and -- CLINICAL MEASUREMENT OF OCULAR BLOOD FLOW Alon Harris, Ingrida Januleviciene, Brent Siesky, Leo Schmetterer, Larry Kageman, Ingeborg Stalmans, Ali Hafez, Makoto Araie, Chris Hudson, John Flanagan, Subha Venkataraman, Edward Gilmore, Gilbert Feke, David Huang, Einar Stefánsson -- Color Doppler Imaging -- Laser Doppler Flowmetry and Scanning Laser Flowmetry -- Retinal Vessel Analyzer -- Blue Field Entoptic Stimulation -- Laser Interferometric Measurement of Fundus Pulsation -- Dynamic Contour Tonometry and Ocular Pulse Amplitude -- Pulsatile Ocular Blood Flow (POBF) Analyzer -- Laser Speckle Method (Laser Speckle Flowgraphy) -- Digital Scanning Laser Ophthalmoscope Angiography -- Bi-directional Laser Doppler Velocimetry and Simultaneous Vessel -- Doppler Optical Coherence Tomography -- Retinal Oximetry -- CLINICAL RELEVANCE OF -- What is the evidence supporting a role for ocular blood flow -- Clinical evidence derived from different measurement parameters -- 1.C Evidence from experimental animal studies -- What disease mechanisms lead to impaired blood flow in glaucoma? -- Ocular versus systemic causes -- Systemic factors -- Vascular dysregulation/perfusion instability -- What is the impact of medication and other modifiable factors on -- IOP-lowering topical medication -- Systemic drugs -- Ocular surgery, exercise -- Does modulation of blood flow alter glaucoma progression? -- 4. Glaucoma and systemic vascular disease.

Systemic disease and glaucoma patients -- Diabetes -- Cardiovascular diseases -- SHOULD MEASUREMENTS OF OCULAR BLOOD -- Interpreting clinical studies -- WHAT DO WE STILL NEED TO KNOW? Alon Harris, Felipe Medeiros, Rita Ehrlich, Vital Costa, Brent Siesky, Ingrida Januleviciene, Claude Burgoyne -- Ocular blood flow and visual function in glaucoma patients -- Ocular perfusion pressure and prevalence and progression of glaucoma -- Ocular blood flow and optic nerve head structure -- The relationship between intraocular pressure and ocular blood flow -- The relationship between cerebrospinal fluid pressure and glaucoma -- Future research -- SUMMARY CONSENSUS POINTS -- INDEX OF AUTHORS.