Cover image for Alkaloids chemical and biological perspectives. Volume 10
Alkaloids chemical and biological perspectives. Volume 10
Title:
Alkaloids chemical and biological perspectives. Volume 10
Author:
Pelletier, S. W. (William), 1924-
ISBN:
9780080427911
Publication Information:
Oxford : Pergamon, 1996.
Physical Description:
xiv, 430 p. : ill. ; 24 cm.
Contents:
Alkaloids from Australian Flora (I.R.C. Bick). Pyridine and Piperidine Alkaloids: An Update (M.J. Schneider). 3-Alkylpiperidine Alkaloids Isolated from Marine Sponges in the Order Haplosclerida (R.J. Andersen et al.). &bgr;-Carboline and Isoquinoline Alkaloids from Marine Organisms (B.J. Baker). Subject Index. Organism Index.
Abstract:
Volume 10 of this series presents four timely reviews. Chapter 1 provides a fascinating account of the history of alkaloid discovery in Australia beginning with the isolation of the first alkaloid from an Australian plant, the Tasmanian sassafras <IT>(Atherosperma moschatum),</IT> by Zeyer in 1861. Also included is a comprehensive survey of alkaloid-bearing plants, and a section dealing with detection, estimation, extraction, and work-up procedures for alkaloids.<P>Chapter 2 provides a comprehensive update to the chapter on "Pyridine and Piperidine Alkaloids" which appeared in volume 3 of this series. The focus of this chapter is on new alkaloids isolated, biosynthesis, and biological properties.<P>Chapter 3 looks at "3-Alkylpiperidine Alkaloids Isolated from Marine Sponges in the Order Haplosclerida". Studies over the past thirty years have shown that sponges are a rich source of alkaloids. Many of these sponge alkaloids are related to each other by the presence of a 3-alkylpiperidine moiety in their structures and it happens that the sponges that have been reported to contain 3-alkylpiperidine alkaloids are all in the order Haplosclerida.<P>Chapter 4 reviews &bgr;-carboline and isoquinoline alkaloids which are pharmacologically some of the most significant marine natural products. This chapter treats the isolation, structure elucidation, synthesis, biosynthesis, and pharmacological activity of these alkaloids.
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