Analysis of temporal and spatial expression of drosophila embryonic small rnas by deep-sequencing method
tarafından
Coşacak, Mehmet İlyas.
Başlık
:
Analysis of temporal and spatial expression of drosophila embryonic small rnas by deep-sequencing method
Yazar
:
Coşacak, Mehmet İlyas.
Yazar Ek Girişi
:
Coşacak, Mehmet İlyas.
Yayın Bilgileri
:
[s.l.]: [s.n.], 2012.
Fiziksel Tanımlama
:
x, 46 leaves. : ill. + 1 computer laser optical disc.
Özet
:
The world of small RNAs is expanding and new types of small RNAs are being identified. By using deep-sequencing techniques in addition to most abundant small RNAs; miRNA and siRNA, piRNA and tRFs were further characterized and shown to be functional. The global behavior of small RNAs during MZT and their location in the cytoplasmic complexes has not been shown. By combining polysomal fractionation and deep-sequencing technique as well as the highly regulated developmental stages in Drosophila we have shown that the temporal and spatial expression of small RNAs changes during MZT. We have shown that each small RNA group has unique behaviour in cytoplasm and is enriched in specific polysomal fractions which shows that their local function in cytoplasmic complexes is mainly translational machinery.
Konu Başlığı
:
RNA editing.
Drosophila melanogaster.
Yazar Ek Girişi
:
Akgül, Bünyamin.
Tüzel Kişi Ek Girişi
:
İzmir Institute of Technology. Molecular Biology and Genetics.
Tek Biçim Eser Adı
:
Thesis (Master)--İzmir Institute of Technology: Molecular Biology and Genetics.
İzmir Institute of Technology: Molecular Biology and Genetics.
Elektronik Erişim
:
Library | Materyal Türü | Demirbaş Numarası | Yer Numarası |
---|
IYTE Library | Tez | T001033 | QH450.25 .C834 2012 |