Aim of the present thesis is to investigate impact trade liberalization on the evolution of regional income inequalities in Turkey between 1975 and 2011. Despite the large body of literature on this subject, there exist several directions which need to be furthert explored . i. so far in the literatur, the concept of trade openness is too broadly defined, However, it is not only 'trade' per se that can affect the regional economies but the composition of trade is also of great importance (Rodriquez-Pose and Gill, 2006). Indeed, it can be partitioned into several components, such as exports and imports (or manufacturing and agricultural trade) We analyze separately the impact of each component on the evolution of regional inequalities. ii. in most of the empirical studies dealing with this issue, neighboring regions are assumed to have no spatial economic interconnection between each other. We, therefore, incorporate spatial spillovers of trade and growth into our analysis.Our results can be summarized in three groups: First, regional inequalities tend to decline over the period of analysis. Second, initially poorer regions that experience an export-based liberalization (particularly in manufacturing goods, not in agricultural goods) trnd to grow faster than richer ones. Imports, on the other hand, heve an opposite effect. Third, the spatial spillovers of growth are found to evident across regions. Such that, growth in a region spilled over to the neighboring ones, positively.