Magnetic manipulation of gravitational force during cell culture
tarafından
 
Kaptan, Sinem, author.

Başlık
Magnetic manipulation of gravitational force during cell culture

Yazar
Kaptan, Sinem, author.

Yazar Ek Girişi
Kaptan, Sinem, author.

Fiziksel Tanımlama
xi, 60 leaves: charts;+ 1 computer laser optical disc.

Özet
With the development of space technologies, one of the most important problems that astronauts will encounter in the planned manned space travels to the Moon and Mars in the near future is the reduced (<1g) gravitational force. Knowledge of the biological effects of partial gravitational force on long-duration space missions is limited. Therefore, it is important to investigate effects of partial gravitational force on physiological adaptation mechanisms. However, methodology to induce partial gravity is expensive and subjected to ethical constraints, therefore there is a need for new ground-based simulation platforms that are able to mimic the partial gravitational force. In this master's thesis, a new partial gravity platform was developed that manipulates gravitational force during cell culture using magnetic fields. First, the platform system was designed and fabricated, and then detailed protocols were described for its use in cell culture. In addition, the effect of simulated partial gravity on cell viability and morphology at the cellular level was examined. The results show that the simulated partial gravity of Mars and the Moon affects the viability and morphology of cells. This new low-cost and easy-to-use partial gravity platform can be used as a ground-based simulation system for gravitational space biology research at the cellular and molecular levels.

Konu Başlığı
Gravity.
 
Space biology
 
Bone cells
 
Cell culture.

Yazar Ek Girişi
Özçivici, Engin,

Tüzel Kişi Ek Girişi
İzmir Institute of Technology. Bioengineering.

Tek Biçim Eser Adı
Thesis (Master)--İzmir Institute of Technology:Bioengineering.
 
İzmir Institute of Technology:Bioengineering --Thesis (Master).

Elektronik Erişim
Access to Electronic Versiyon.


LibraryMateryal TürüDemirbaş NumarasıYer NumarasıDurumu/İade Tarihi
IYTE LibraryTezT002639QH585.2 .K17 2022Tez Koleksiyonu