Ethno-psychopharmacology : Advances in Current Practice.

Cover -- Half-title -- Title -- Copyright -- Contents -- Figures -- Tables -- Contributors -- Foreword -- Acknowledgments -- 1 Introduction -- 2 Culture and psychopathology -- Introduction -- Some concepts used in transcultural research -- Culture -- Race -- Ethnicity -- Acculturation -- Adaptation -- Relation between the two cultures -- Influence of culture on the prevalence and expression of symptoms -- The Hutterites -- Neurasthenia in China -- Ataque de nervios -- Culture-bound syndromes -- Cultural contributions to DSM-IV -- Current perspectives in psychiatric diagnosis -- Therapeutic response to treatments -- Conclusion -- REFERENCES -- 3 Culture and ethnicity in psychopharmacotherapy -- Introduction -- Drug-metabolizing enzymes -- Diet and its effect on P450 enzymes -- Smoking and its effect on P450 enzymes -- Genetic polymorphisms in gene encoding receptors, transporters, or other therapeutic targets -- Non-biologic factors that affect drug response -- Conclusion -- REFERENCES -- 4 Ethnic differences in psychotropic drug response and pharmacokinetics -- Introduction -- Genetic factors influencing drug response -- Non-genetic factors influencing drug responses: dietary and sociocultural -- Pharmacogenetic differences in drug metabolism -- Drug-metabolizing enzymes -- Ethnic differences in medication metabolism -- Antidepressant ethnic differences -- Pharmacokinetic differences -- Pharmacodynamic differences -- Benzodiazepine ethnic differences -- Antipsychotic ethnic differences -- Pharmacokinetic differences -- First-generation antipsychotics -- Second-generation antipsychotics -- Clozapine -- Olanzapine -- Risperidone -- Aripiprazole -- Ziprasidone -- Quetiapine -- Amisulpride -- Drug-drug interactions -- Pharmacodynamic differences -- Conclusion -- REFERENCES -- 5 Pharmacogenetics of ethnic populations -- Introduction.

Pharmacodynamic aspects -- Genetic studies of antidepressants -- Serotonin transporter -- Tryptophan hydroxylase -- Serotonin receptor 2A -- Serotonin receptor 6 -- G-protein b3 subunit -- Norepinephrine transporter -- Genetic studies of mood stabilizers -- Genetic studies of antipsychotic drugs -- Cytochrome P450 -- CYP2D6 -- CYP2C19 -- Conclusions -- REFERENCES -- 6 Variation in psychotropic responses in the Chinese population -- Psychopharmacotherapy in the Chinese population -- Variations in the pharmacokinetics and pharmacodynamics of psychotropics in the Chinese population -- The clinical responses of psychotropic drugs in Chinese populations -- Concluding remarks -- REFERENCES -- 7 Variation in psychotropic responses in the Hispanic population -- Introduction -- Antidepressants -- Tricyclics -- Selective serotonin re-uptake inhibitors (SSRIs) -- Selective serotonin and norepinephrine re-uptake inhibitors -- Antipsychotics -- Racial discrepancies in the use of second-generation antipsychotics (SGAs) -- Efficacy and safety -- Metabolic syndrome, diabetes, and hispanics -- Pharmacogenetics and the Mexican American population -- Drug-diet and drug-herbal interactions -- Conclusions -- REFERENCES -- 8 Identifying inter-ethnic variations in psychotropic response in African Americans and other ethnic minorities -- Introduction -- Biological factors and clinical implications -- Research participation -- Conclusion -- REFERENCES -- 9 Complementary medicines in mental disorders -- REFERENCES -- 10 Cultural factors and the use of psychotropic medications -- Culture and attitudes towards medications -- Medication compliance in pharmacotherapy -- Measurement of attitudes towards psychotropic drugs -- Summary -- REFERENCES -- 11 Outpatient prescribing practices in Asian countries -- Introduction -- Antipsychotics prescribing -- Antidepressant prescribing.

Anxiolytics and hypnotics prescribing -- Summary -- REFERENCES -- 12 Psychiatric inpatient psychotropic prescribing in East Asia -- Introduction -- Psychotropic prescribing patterns -- Antipsychotic drugs -- Types -- Dosages -- Antidepressants -- Antianxiety and hypnotic/sedative drugs -- Antiparkinson drugs -- Mood stabilizers -- Discussion -- Conclusion -- REFERENCES -- 13 Pharmaco-economic implications for Asia and other economically disadvantaged countries -- Introduction -- The problems -- Priorities and hopes for the future -- Coda -- REFERENCES -- 14 Integrating theory, practice and economics in psychopharmacology -- New drug discovery approaches -- Maximizing effectiveness in practice settings -- Clinical application of pharmacogenomics and individualized medicine -- Application of pharmaco-economics in psychopharmacology -- Conclusion -- REFERENCES -- 15 Research directions in ethno-psychopharmacology -- Ethno-psychopharmacology in the new era of pharmacogenetics -- Aiming for an integrated model of ethno-psychopharmacology -- Future research directions -- Conclusions -- REFERENCES -- Index.