Cognitive Science Compendium. Volume 2.

COGNITIVE SCIENCE COMPENDIUM, VOLUME 2 -- COGNITIVE SCIENCE COMPENDIUM, VOLUME 2 -- LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA -- CONTENTS -- PREFACE -- Chapter 1: SUBCELLULAR TRAFFICKING OF BACE1: MOLECULAR MECHANISMS IN THE CONTROL OF β-AMYLOID GENERATION -- ABSTRACT -- INTRODUCTION -- PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL FUNCTIONS OF THE β-SECRETASE BACE1 -- THE SUBCELLULAR TRANSPORT OF BACE1 -- THE ROLE OF THE CYTOPLASMATIC DOMAIN OF BACE1 IN ITS SUBCELLULAR TRAFFICKING -- HOW COULD GGA 1 DEPENDENT TRAFFICKING OF BACE1 INFLUENCE Aβ GENERATION ? -- CONCLUSIONS -- ACKNOWLEDGEMENTS -- REFERENCES -- Chapter 2: BRAIN VESICULAR MONOAMINE TRANSPORTER AND APOPTOSIS: PERSPECTIVES ON DEVELOPMENT AND NEURODEGENERATION -- ABSTRACT -- INTRODUCTION -- VMAT2 VERSUS MONOAMINE OXIDASE -- DEVELOPMENTAL EXPRESSION OF VMAT2 -- MICE LACKING VMAT2 -- VMAT2 AND PROGRAMMED CELL DEATH IN THE CEREBRAL CORTEX -- PARKINSON'S DISEASE -- SPONSORS -- REFERENCES -- Chapter 3: MILD COGNITIVE IMPAIRMENT IS TOO LATE: THE CASE FOR PRESYMPTOMATIC DETECTION AND TREATMENT OF ALZHEIMER'S DISEASE -- ABSTRACT -- 1. INTRODUCTION -- 2. THE BRAIN RESERVE HYPOTHESIS -- 3. NEURONAL PLASTICITY -- 4.MILD COGNITIVE IMPAIRMENT (MCI) AND ALZHEIMER'S DISEASE (AD) -- 5. PRESYMPTOMATIC DETECTION OF MCI AND AD -- 6. OVERALL SUMMARY AND CONCLUSIONS -- ACKNOWLEDGEMENTS -- REFERENCES -- Chapter 4: SEMANTICALLY MEDIATED INTEGRATION OF COGNITION IN HOMO SAPIENS: EVOLUTION, GRAMMAR, UNCERTAINTY, AND COGNITIVE ACCURACY -- ABSTRACT -- INTRODUCTION -- BRAIN, BONDING, LANGUAGE, CULTURE, AND EVOLUTION -- HUMAN BRAIN MODEL -- HUMAN BRAIN AND COGNITIVE DEVELOPMENT -- AUTHOR NOTES -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5: EXPLORING THE PAST AND IMPENDING FUTURE IN THE HERE AND NOW: MIND-WANDERING IN THE DEFAULT STATE -- ABSTRACT -- INTRODUCTION -- MATERIALS AND METHODS.

OBTAINING MEASURES OF IMPENDING FUTURE AND PAST-ORIENTED MIND-WANDERING -- ASSESSING THE STABILITY OF PEOPLE'S IMPENDING FUTURE AND PAST-ORIENTED MIND-WANDERING -- PHASE 1: ESTABLISHING HIGH INCIDENCE MIND-WANDERING PERIODS -- PHASE 2: THOUGHT-SAMPLING (DAY 4) -- PHASE 3: IDENTIFYING NEURAL CORRELATES OF PAST AND IMPENDING FUTURE MIND-WANDERING -- DISCUSSION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 6: CONTROL OF CORTICAL SYNAPTIC RECEPTIVE FIELDS BY NEUROMODULATION AND PATTERNED SENSORY INPUT -- ABSTRACT -- INTRODUCTION -- CORTICAL RECEPTIVE FIELD ORGANIZATION -- CORTICAL RECEPTIVE FIELD PLASTICITY -- NEUROMODULATION AND RECEPTIVE FIELD PLASTICITY -- IMPLICATIONS OF CORTICAL PLASTICITY TO OVERALL BRAIN FUNCTION -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 7: LINKS BETWEEN DOWN SYNDROME AND ALZHEIMER'S DISEASE -- ABSTRACT -- INTRODUCTION -- PATHOLOGICAL FEATURES OF AD IN DS PATIENTS -- CANDIDATE GENES ON CHROMOSOME 21 THAT LINK DS AND AD -- CONCLUSION AND SUMMARY -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 8: CHOLESTEROL, SECRETASE ACTIVITIES, AND Aβ PRODUCTION IN ALZHEIMER'S PATHOGENESIS -- ABSTRACT -- I. INTRODUCTION -- II. SECRETASES AND PROCESSING PATHWAYS FOR APP -- III. CHOLESTEROL AND ALZHEIMER'S DISEASE -- IV. SUMMARY -- ACKNOWLEDGMENTS -- REFERENCES -- INDEX.