Investigation of microbial biofilm formation using electrochemical impedance spectroscopy and equivalent circuit modelling için kapak resmi
Investigation of microbial biofilm formation using electrochemical impedance spectroscopy and equivalent circuit modelling
Kuş, Anılcan, author.
Yazar Ek Girişi:
Fiziksel Tanımlama:
xii, 57 leaves: charts;+ 1 computer laser optical disc
Bacterial biofilm is like a cooperative form of planktonic bacteria that colonize to acquire more nutritious and become resistant to surroundings. The communal organization results from the connection of bacteria by polysaccharides, lipids, or the extracellular matrix, which can provide a protective environment for living cells and communicate between them or allow specific types of chemicals inside through the matrix. 60%-80% of the infections are known to be biofilm-related. Bacterial biofilms are more resistant to antibiotics, and treating them with the wrong antibiotics might result in a thicker biofilm. In order to overcome these difficulties and researching new treatments for biofilm inflammation understanding the formation process is essential. For this manner, Electrochemical Impedance Spectroscopy (EIS) has potential uses in various fields such as biosensors, corrosion studies, healthcare owing to its facile operation and affordable devices to conduct electroanalysis. EIS calculates the excitation voltage and current generated with the oscillating frequency. Developing impedimetric methods are gaining attention due to the operation being label-free. Considering its labelfree nature, EIS is a possible candidate to explain the electrodynamics of living systems such as cell-matrix interaction, biofilm formation in vitro. Detection of those is essential to prevent infections and to develop medical needs to cure them. The thesis focuses on understanding the electrodynamics of bacterial biofilm formation via electrochemical methods such as square wave voltammetry (SWV), Open Circuit Potential (OCP), and EIS. After carrying out the experiments, time-dependent circuit models for EIS were built, and the data were extracted to demonstrate changes in the bacterial system.
Yazar Ek Girişi:
Tek Biçim Eser Adı:
Thesis (Master)--İzmir Institute of Technology:Materials Science and Engineering.

İzmir Institute of Technology: Materials Science and Engineering--Thesis (Master).
Elektronik Erişim:
Access to Electronic Versiyon.


Materyal Türü
Demirbaş Numarası
Yer Numarası
Durumu/İade Tarihi
Tez T002387 QR46 .K971 2021

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