Development of a telemedicine platform for remote monitoring of patients

Telemedicine supports patients and healthcare professionals to provide remote medical services and to ensure that medical operations, services, and applications. Telemedicine provides mobile health services, doctor-patient communication, relationship and consultation, medical clinic, and operation service for the diagnosis, monitoring, treatment, and rehabilitation by remote health services. In this thesis, telemedicine-based applications and integrated devices are developed to assist in the diagnosis, monitoring, and treatment processes of specific diseases. In this regard, a WebRTC-based telemedicine application has been developed to ensure the transfer of health data and doctor-patient communication for monitoring diseases. The developed telemedicine application performance of providing doctor-patient communication and its effect on the management of chronic heart failure disease were examined. Thereupon, medical diagnosis and wearable devices have been developed that can be integrated into the telemedicine application that has been proven for disease monitoring. As part of this study, vital health data, biomarkers, and pathogen analysis were performed by developed devices to diagnose and monitor three chronic diseases, namely sleep apnea, chronic kidney disease, and COVID-19. First, a wearable device platform has been developed that can analyze breathing patterns via diaphragm acceleration and breath temperature and diagnose and monitor sleep apnea. Afterward, electromechanical LOC platforms used for colorimetric determination of serum creatinine levels for the diagnosis of chronic kidney disease by two methods were characterized and presented in detail. Finally, a realtime LAMP-based electromechanical device used to detect SARS-CoV-2 viral RNA has been produced, and a colorimetric rapid test system has been developed and tested for COVID-19 diagnosis. In this way, devices and systems integrated into the telemedicine platform have been developed for use in different diseases and medical applications. With these developed platforms, disease diagnosis, treatment and rehabilitation, remote monitoring and patient management are provided with inexpensive, portable, userfriendly, easy-to-use solutions without the need for professional service providers.