Organophosphorus Chemistry -- Contents -- Chapter 1 Phosphines and Phosphonium Salts -- 1. Phosphines -- 1.1. Preparation -- 1.1.1 From Halogenophosphines and Organometallic Reagents -- 1.1.2. Preparation of Phosphines from Metallated Phosphines -- 1.1.3 Preparation of Phosphines by Addition of P-H to Unsaturated Compounds -- 1.1.4 Preparation of Phosphines by Reduction -- 1.1.5 Miscellaneous Methods of Preparing Phosphines -- 1.2 Reactions of Phosphines -- 1.2.1 Nucleophilic Attack at Carbon -- 1.2.2 Nucleophilic Attack at Halogen -- 1.2.3 Nucleophilic Attack at Other Atoms -- 1.2.4 Miscellaneous Reactions of Phosphines -- 2 Phosphine Oxides -- 2.1 Preparation -- 2.2 Reactions -- 2.3 Structural and Physical Aspects -- 2.4 Phosphine Chalcogenides as Ligands -- 3 Phosphonium Salts -- 3.1 Preparation -- 3.2 Reactions -- 4 pπ-Bonded Phosphorus Compounds -- 5 Phosphirenes, Phospholes and Phosphinines -- References -- Chapter 2 Pentaco-ordinated and Hexaco-ordinated Compounds -- 1 Introduction -- 2 Acyclic and Monocyclic Phosphoranes -- 3 Bicyclic and Tricyclic Phosphoranes -- 4 Pentaco-ordinate/Hexaco-ordinate Compounds -- References -- Chapter 3 Tervalent Phosphorus Acid Derivatives -- 1 Introduction -- 2 Reactions Involving Nucleophilic Phosphorus -- 3 Reactions Involving Electrophilic Phosphorus -- 4 Miscellaneous Reactions -- References -- Chapter 4 Quinquevalent Phosphorus Acids -- 1 Introduction -- 2 Phosphoric Acids and their Derivatives -- 2.1 Synthesis of Phosphoric Acids and their Derivatives -- 2.2 Reactions of Phosphoric Acids and their Derivatives -- 2.3 Selected Biological Aspects -- 3 Phosphonic and Phosphinic Acids -- 3.1 Synthesis of Phosphonic and Phosphinic Acids and their Derivatives -- 3.1.1 Alkyl, Cycloalkyl, Aralkyl and Related Acids -- 3.1.2 Alkenyl, Alkynyl, Aryl, Heteroaryl and Related Acids.

3.1.3 Halogenoalkyl and Related Acids -- 3.1.4 Hydroxyalkyl and Epoxyalkyl Acids -- 3.1.5 Oxoalkyl Acids -- 3.1.6 Aminoalkyl and Related Acids -- 3.1.7 Sulfur- and Selenium-containing Compounds -- 3.1.8 Phosphorus-Nitrogen Bonded Compounds -- 3.1.9 Phosphorus-containing Ring Systems -- 3.2 Reactions of Phosphonic and Phosphinic Acids and their Derivatives -- 3.3 Selected Biological Aspects -- 4 Structure -- References -- Chapter 5 Nucleotides and Nucleic Acids -- 1 Introduction -- 2 Mononucleotides -- 2.1 Nucleoside Acyclic Phosphates -- 2.1.2. Mononucleoside Phosphate Derivatives -- 2.1.3. Polynucleoside Monophosphates -- 2.2 Nucleoside Cyclic Phosphates -- 3 Nucleoside Polyphosphates -- 4 Oligo- and Poly-nucleotides -- 4.1 DNA Synthesis -- 4.2 RNA Synthesis -- 4.3 The Synthesis of Modified Oligodeoxynucleotides and Modified Oligoribonucleotides -- 4.1.4. Oligonucleotides Containing Modified Phosphodiester Linkages -- 4.3.2 Oligonucleotides Containing Modified Sugars -- 4.3.3 Oligonucleotides Containing Modified Bases -- 5 Linkers -- 6 Interactions and Reactions of Nucleic Acids with Metal Ions -- 7 Nucleic Acid Devices -- 8 Nucleic Acid Structures -- References -- Chapter 6 Ylides and Related Species -- 1 Introduction -- 2 Phosphonium Ylides -- 2.1 Theoretical and Mechanistic Studies of Phosphonium Ylides and the Wittig Reaction -- 2.2 Synthesis and Characterisation of PhosphoniumYlides -- 2.3 Ylides Coordinated to Metals -- 2.4 Reactions of Phosphonium Ylides -- 2.4.1 Reactions with Carbonyl Compounds -- 2.4.2 Reactions of Aza-Wittig Reagents -- 2.4.3 Miscellaneous Reactions -- 3 Synthesis and Reactions of Phosphonate Anions -- 4 Structure and Reactivity of Lithiated Phosphine Oxide Anions -- 5 Selected Applications in Synthesis -- 5.1 Compounds with Potential Biological Properties -- 5.2 Solid Phase Synthesis.

5.3 Tetrathiafulvalenes and Related Organic Materials -- 5.4 Synthesis of Miscellaneous Compounds -- References -- Chapter 7 Phosphazenes -- 1 Introduction -- 2 Linear Phosphazenes -- 3 Cyclophosphazenes -- 4 Polyphosphazenes -- 5 Crystal Structures of Phosphazenes and Related Compounds -- References -- Chapter 8 Physical Methods -- 1 Theoretical and Molecular Modelling Studies -- 1.1 Studies Based on Semiempirical Methods -- 1.2 Studies Based on Ab initio and Density Functional Methods -- 2 Nuclear Magnetic Resonance Spectroscopy -- 2.1 Biological and Analytical Applications -- 2.2 Applications of 31P NMR Chemical Shifts and Shielding Effects -- 2.2.1 One-coordinate Compounds -- 2.2.2 Two-coordinate Compounds -- 2.2.3 Three-coordinate Compounds -- 2.2.4 Four-coordinate Compounds -- 2.2.5 Five-coordinate Compounds -- 2.2.6 Six-coordinate Compounds -- 2.2.7 Other Nuclei/Multinuclear/General NMR -- 2.3 Studies of Equilibria, Configuration and Conformation -- 2.4 Spin-Spin Couplings -- 3 Electron Paramagnetic (Spin) Resonance Spectroscopy -- 4 Vibrational and Rotational Spectroscopy -- 4.1 Vibrational Spectroscopy -- 4.2 Rotational Spectroscopy -- 5 Electronic Spectroscopy -- 5.1 Absorption Spectroscopy -- 5.2 Fluorescence and Chemiluminescence Spectroscopy -- 5.3 Photoelectron Spectroscopy -- 6 X-Ray Structural Studies -- 6.1 X-Ray Diffraction (XRD) -- 6.1.1 Two-coordinate Compounds -- 6.1.2 Three-coordinate Compounds -- 6.1.3 Four-coordinate Compounds -- 6.1.4 Five- and Six-coordinate Compounds -- 6.2 X-Ray Absorbtion Near Edge Spectroscopy (XANES) -- 6.3 Electron Diffraction -- 7 Electrochemical Methods -- 7.1 Dipole Moments -- 7.2 Cyclic Voltammetry and Polarography -- 7.3 Potentiometric Methods -- 8 Thermochemistry and Thermal Methods -- 9 Mass Spectroscopy -- 10 Chromatography and Related Techniques.

10.1 Gas Chromatography and Gas Chromatography-Mass Spectroscopy (GC-MS) -- 10.2 Liquid Chromatography -- 10.2.1 High-performance Liquid Chromatography and LC-MS -- 10.2.2 Thin-layer Chromatography (TLC) -- 10.3 Capillary Electrophoresis (CE) and Micellar ElectrokineticChromatography (MEKC) -- 11 Kinetics -- References -- Author Index.