
Gene Families : Studies of Dna, Rna, Enzymes & Proteins.
Başlık:
Gene Families : Studies of Dna, Rna, Enzymes & Proteins.
Yazar:
Xue, Gouxiong.
ISBN:
9789812810557
Yazar Ek Girişi:
Fiziksel Tanımlama:
1 online resource (328 pages)
İçerik:
CONTENTS -- Preface -- Obituary -- Clement Markert -- Identification of Novel Gene Family Members Based on Efficient Full-Length cDNA Cloning -- 1 Introduction -- 2 Materials and Methods -- 3 Results -- 4 Discussion -- 5 Acknowledgement -- Reference -- Strategies for Testis Specific Gene Expression -- 1 Specific Gene Expression During Spermatogenesis -- 2 Alternative Splice Variants -- 3 Alternative Promoter Usage: Testis Specific Calpastatin (tCAST) -- 4 Unique Gene Expression -- 5 Summary -- 6 Acknowledgements -- References -- Oxidized Isoforms as Diagnostic Biomarkers of Alzheimer's Disease -- 1 Introduction -- 2 Results -- 3 Conclusions -- 4 Acknowledgements -- References -- Transgenic Fish and Biosafety -- 1 Introduction -- 2 Gene Transfer in Fish -- 3 The Biosafety of Transgenic Fish -- 4 The Prospect of Transgenic Fish -- 5 Acknowledgements -- References -- Aldehyde Dehydrogenases of Human Corneal and Lens Epithelial Cells -- 1 Introduction -- 2 Transmission of Visible Light and the Absorption of UV Radiation by Anterior Eye Tissues -- 3 ALDHs are Major Soluble Proteins of Human Corneal and Lens Epithelial Cells -- 4 Ocular ALDH Substrate Specificities -- 5 Proposed Roles for Corneal and Lens ALDHs as Major Soluble Proteins and in the Metabolism of Peroxidic Aldehydes -- 6 Summary -- 7 Acknowledgements -- References -- X-Chromosome Inactivation During Spermatogenesis: The Original Dosage Compensation Mechanism in Mammals? -- 1 Introduction -- 2 X-Chromosome Activity During Eutherian Development -- 3 X-Linked Gene Expression During Spermatogenesis in Eutherians -- 4 Regulation of Eutherian XCI -- 5 X-Chromosome Activity and Dosage Compensation in Marsupials -- 6 Hypothesis -- References -- Molecular Evolution and Environmental-Stress -- 1 Introduction -- 2 Evidence -- 3 Theory -- 4 Acknowledgements -- References.
Nitric Oxide Related Enzymes and Coronary Artery Disease -- 1 Nitric Oxide - A Double Edged Sword Effects on Atherogenesis -- 2 Nitric Oxide and Oxidative Stress -- 3 Interactive Effects of Cigarette Smoking and Nitric Oxide on Endothelial Dysfunction -- 4 Associations Between eNOS Polymorphisms and Vascular Disease -- 5 Population Diversity in Associating eNOS Polymorphisms and Vascular Disease -- 6 Effect of eNOS Polymorphisms on Gene Expression and Nitric Oxide Production -- 7 Summary -- References -- Pathways, Compartmentation and Gene Evolution -- 1 Introduction -- 2 Methods -- 3 Results -- 4 Discussion -- 5 Acknowledgements -- References -- Tomato CF Genes for Resistance to Cladosporium fulvum -- 1 Introduction -- 2 The Tomato-Cladosporium fulvum Interaction -- 3 Tomato Cf Genes -- 4 Cf Gene Isolation -- 5 Chromosomal Organization of the Cf-4/Cf-9 and Cf-2/Cf-5 Loci -- 6 Recombination at Cf Gene Loci -- 7 Cf Genes Encode Extracellular Membrane-Anchored LRR Glycoproteins -- 8 Cf Protein Structure -- 9 Recognition Specificity of Cf Proteins -- 10 Discussion -- 11 Acknowledgements -- References -- Gene Expression and Intermolecular Forces in Estrogen/Receptor Binding -- 1 Introduction -- 2 Methods -- 3 Gene Expression or Inhibition Due to Estrogen Binding with Receptors -- 4 Discussion -- 5 Acknowledgments -- References -- Probing for the Basic of the Low Activity of the Oriental Variant of Liver Mitochondral Aldehyde Dehydrogenase -- 1 Introduction -- 2 Methods -- 3 Results and Discussion -- 4 Acknowledgements -- References -- S RNases and Self and Non-self Pollen Recognition in Flowering Plants -- 1 Introduction -- 2 Gametophytic Self-Incompatibility and S RNases -- 3 Approaches to Clone Pollen S Gene in Antirrhinum -- 4 Perspectives -- 5 Acknowledgements -- References.
The Roles of Carbonic Anhydrase Isozymes in Cancer -- 1 Introduction -- 2 CA Isozymes and Cell Growth -- 3 CA Isozymes and Tumour Invasion -- 4 Inactive CA Isoforms and Oncogenesis -- 5 CA Isozymes as Tumour Markers -- 6 Concluding Comments -- References -- Biochip and Miniaturization -- 1. Introduction -- 2. Sample Preparation -- 3. Biochemical Reaction -- 4. Detection -- 5. Integration -- References -- Functional Genomics: A Platform for the Discovery of New Therapies -- 1 Comprehensive Functional Genomics Platforms -- 2 Studying Transcription Regulation and Cell Cycle Control Employing Functional Genomics Approaches -- 3 Conclusion -- References -- A Novel Mathematical Analysis of Human Leukocyte Antigen (HLA) Polymorphism -- 1 Introduction -- 2 Material and Methods -- 3 Results and Discussion -- 4 Acknowledgment -- References -- Characterization of a New Tissue-Specific Mutation of the Yellow Gene Which Supports Transvection -- 1 Introduction -- 2 Materials and Methods -- 3 Results and Discussion -- 4 Acknowledgment -- References -- MHC Class II Suppression by Trophoblast cDNAs -- 1 Introduction -- 2 Method -- 3 Results -- 4 Discussion -- 5 Acknowledgements -- References -- Null Activity Mutation of Phenoloxidase in Drosophila melanogaster -- 1 Introduction -- 2 Native Polyacrylamide Gel Electrophoresis -- 3 RT-PCR and DNA Sequencing -- 4 Functional Aspect of MoxGm95 -- 5 Acknowledgments -- References -- Molecular Information Fusion for Metabolic Networks -- 1 Introduction -- 2 Modelling of Metabolic Networks -- 3 Information Fusion -- 4 The Biomedical Workbench -- 5 Logical Integration of Molecular Databases -- 6 Summary and Outlook -- 7 Acknowledgements -- References.
Intron-Size and Exon Polymorphisms in the Mouse Tissue-Nonspecific Alkaline Phosphatase Gene -- 1 Introduction -- 2 Materials and Methods -- 3 Results and Discussion -- 4 Acknowledgments -- References -- Lipoxygenases and Cyclooxygenases of the Testis of Rat -- 1 Introduction -- 2 Methodology -- 3 Results and Discussion -- 4 Acknowledgements -- References -- Effect of Heterogeneous Sperm and Hybridization of DNA Fragment in Allogynogenetic Silver Crucian Carp -- 1 Introduction -- 2 Results -- 3 Prospect -- Reference -- Gene Expression During Carrot Somatic Embryogenesis -- 1 Introduction -- 2 Isolation of Somatic Embryogenesis Related Genes from Carrot -- 3 Effects of Sucrose Regulation Culture on Endogenous ABA Levels of Carrot Somatic Embryo -- 4 Gene cloning of LEA protein from carrot and analysis of its expression features -- 5 Acknowledgement -- References -- Epigenetic Modifications in Maize Parental Inbreds and Hybrids and their Relationship to Hybrid Vigor and Stability -- 1 Introduction -- 2 DNA Methylation in Maize -- 3 Changes of DNA Methylation during Maize Development -- 4 The Effects of Growth Conditions -- 5 Site-specific Methylation Changes Induced by Stress -- 6 Conclusion -- References -- CIS-Elements and Transcription Factors Regulating Antioxidant Gene Expression in Response to Biotic and Abiotic Signals -- 1 Introduction -- 2 Formation of Reactive Oxygen Species -- 3 Toxic Effects of Oxygen Free Radicals -- 4 The Maize Antioxidant Defense Genes: A Model System -- 5 ROS Production by Environmental Stresses -- 6 Molecular Mechanisms in Response to ROS -- 7 Structure of the Promoter Region of the Maize Cat Genes -- 8 Cat genes Respond Differentially to Environmental Stresses -- 9 Expression of Cat1::Gus Constructs in Maize Culture Cells and in Intact Maize Tissues.
10 The ABRE Motif Interacts with Nuclear Proteins Isolated from Embryos -- 11 Cat1 Transcript Increases in Response to Hydrogen Peroxide -- 12 Concluding Comments and Prospects -- 13 Acknowledgment -- References -- Index.
Özet:
This archival volume is an invaluable collection of rigorously reviewed articles by experts in the fields of gene families, DNA, RNA and proteins, to commemorate the passing of a giant of science - Professor Clement L Markert (1917-1999). In 1959, Clement Markert and Freddy Moller developed the concept of the isozyme, which paved the way for extensive studies of enzyme, protein and gene multiplicity across all living organisms. This important scientific discovery has had a profound influence on the biological sciences for more than 40 years, and has provided the basis for regular international meetings to discuss the biological and biomedical implications of enzyme multiplicity. More recently, this concept has been extended to a wide range of gene families of DNA, RNA, proteins and enzymes. Contents: Clement Markert (G L Hammond); Identification of Novel Gene Family Members Based on Efficient Full-Length cDNA Cloning (J Gu et al.); Aldehyde Dehydrogenases of Human Corneal and Lens Epithelial Cells (R S Holmes); X-Chromosome Inactivation During Spermatogenesis: The Original Dosage Compensation Mechanism in Mammals? (J R Mc Carrey); Probing for the Basis of the Low Activity of the Oriental Variant of Liver Mitochondrial Aldehyde Dehydrogenase (B Wei & H Weiner); The Roles of Carbonic Anhydrase Isozymes in Cancer (W R Chegwidden et al.); MHC Class II Suppression by Trophoblast cDNAs (G L Hammond et al.); Molecular Information Fusion for Metabolic Networks (R Hofestädt et al.); Effect of Heterogeneous Sperm and Hybridization of DNA Fragment in Allogynogenetic Silver Crucian Carp (D Xia et al.); Gene Expression During Carrot Somatic Embryogenesis (N Wu); and other papers. Readership: Graduate students, post-docs and experts interested in gene families.
Notlar:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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