Coupling reactions of enyne oxiranes with grignard reagents için kapak resmi
Coupling reactions of enyne oxiranes with grignard reagents
Başlık:
Coupling reactions of enyne oxiranes with grignard reagents
Yazar:
Aytaç, İsmet Arınç, author.
Fiziksel Tanımlama:
xii, 195 leaves:+ 1 computer laser optical disc
Özet:
Laboratory-synthesized (Z)-2,4-Enyne oxiranes were subjected iron-catalyzed reactions with Grignard reagents. The reactions afforded majorly E-configured vinylallenes with a hydroxyl group on the allylic carbon as the 1,5-(SN2'')-substitution products. However, in some case, along with the desired vinyllallenes products, 1,1- (SN2) and 1,3-substitution (SN2’) by-products were also recovered. Diastereo-selectivity of the method is strictly reliant on the syn/anti mode of the alkylation process. This study provides a new methodology for the synthesis of vinylallenes which are potential building blocks of biological active molecules.
Yazar Ek Girişi:
Tek Biçim Eser Adı:
Thesis (Master)--İzmir Institute of Technology: Chemistry.

İzmir Institute of Technology: Chemistry--Thesis (Master).
Elektronik Erişim:
Access to Electronic Versiyon.
Ayırtma: Copies: