Climate change, destruction of the natural environment, high-rise buildings, intense urbanization, and high energy consumption are increasingly making urban living challenging. Climate change triggers this situation, creating an increased urban heat island effect. Outdoor thermal comfort is crucial for pedestrian health in urban areas. The growing heat island effect due to climate change leads to thermal comfort issues in cities, negatively affecting urban life. Different urban forms within cities provide different microclimatic comfort zones for pedestrians. We must adapt urban planning to climate conditions from macro to micro scales with a holistic perspective. This study examines how the heat island effect in the Poligon Stream, and its surrounding area can be reduced using a climate-sensitive design approach. The main purpose of this study is to enhance the urban microclimate around the Poligon Stream by proposing design solutions at various scales to mitigate the urban heat island effect. To calculate land surface temperature and the heat island effect, satellite data from the hottest day of the year 2022 was utilized. Wind and thermal comfort models were developed using meteorological data such as air temperature, global radiation, wind speed, and relative humidity. The morphological structure of the study area, along with the analysis results of meteorological parameters and land surface temperature, indicates that the cooling capacity in the district is considerably low. Due to the heat island effect, urban life reaches levels that adversely affect living conditions in the summer months. Resulting in substantial, sustainable urban design proposals, focusing on ecological, nature-based, and climate-sensitive approach, were developed, resulting in a 13% reduction in the urban heat island effect.