FrontMatter -- Reviewers -- Foreword -- Contents -- Executive Summary -- 1 Introduction -- 2 Overview of HIVNET 012 -- 3 Study Design, Treatment Assignment, and Adherence to Study Regimens -- 4 Efficacy and Safety -- 5 Review of Ethical Issues -- 6 Response to the Charge to the Committee -- Appendixes -- Appendix A Agendas of Information-Gathering Meetings -- Appendix B Comparisons to Other Perinatal HIV Prevention Studies Using NVP and ZDV -- Appendix C Committee Biographies.