Contents -- Contributors -- Preface to Series -- Does Traditional Chinese Medicine Work? -- Chapter 1 Risks of Traditional Chinese Herbal Medicine Edzard Ernst -- 1.1 Introduction -- 1.2 Toxicity of Herbal Ingredients -- 1.3 Aconitum Species (Aconite) -- 1.4 Aristolochia Species -- 1.5 Ephedra Species (Ma Huang) -- 1.6 Ginkgo biloba (Maidenhair Tree) -- 1.7 Ginseng -- 1.8 Glycyrrhiza glabra (Licorice) -- 1.9 Salvia rniltiorrhiza (Danshen) -- 1.10 Tetrahydropalmatine (Jin Bu Huan) -- 1.11 Contamination/Adulteration -- 1.12 TCHM-Drug Interactions -- 1.13 Discussion -- References -- Chapter 2 Research of Acupuncture Ameliorating Psycho-Craving for Patients Dependent on Heroin Jun-mei Wu, Jian-hua Lin, Yong-fen Luo & Jun Li -- 2.1 Introduction -- 2.2 Material -- 2.2.1 Subjects -- 2.2.2 Main reagents and apparatus -- 2.3 Methods -- 2.3.1 Grouping -- 2.3.2 Treatment -- 2.3.3 Observation method -- 2.3.4 Statistics -- 2.4 Results -- 2.4.1 -- 2.5 Discussion -- References -- Chapter 3 Advances in Research of Angiogenesis Effect of Traditional Chinese Medicine Zhi-shan Ding & Xing-de Yuo -- 3.1 Introduction -- 3.2 Angiogenesis and Disease -- 3.2.1 Angiogenesis and tumours -- 3.2.2 Angiogenesis and atherosclerosis -- 3.2.3 Angiogenesis and rheumatoid arthritis -- 3.3 Factors Affecting Angiogenesis -- 3.4 TCM and Angiogenesis -- 3.4.1 Anti-angiogenetic TCM drugs -- 3.4.2 TCM promotion of angiogenesis -- 3.5 Conclusion -- References -- Chapter 4 The Rationale of Combination Drug Formulas in Traditional Chinese Medicine Jie Wang, Lin-guo Zhang & Wei Jia -- 4.1 Introduction -- 4.2 The Study of Combination Drug Formulas and TCM -- 4.3 The Study of Chemical Ingredients in Combination Formulas -- 4.4 Pharmacological Study with Regard to the Rationale and Compatibility of Different Herbal Drugs Selected in a Combination Formula.

4.5 Issues on the Participation of Multidisciplines -- 4.6 Prospects -- References -- Chapter 5 Approaches in Treating AIDS with Chinese Medicine Wei-bo Lu -- 5.1 Introduction -- 5.2 Reductional Analytical Approach -- 5.3 Holistic Balanced Approach -- 5.3.1 Evil versus normal qi (spear versus shield) -- 5.3.2 Immuno-enhancement should be the key -- 5.4 Integrative Complementary Approach -- References -- Chapter 6 Anti-liver Fibrosis with Integrated Traditional Chinese and Western Medicine Ping Liu, Cheng-hai Liu, Cheng Liu, Yi-yung Hu & Lie-ming Xu -- 6.1 Introduction -- 6.2 Clinical Efficacy of TCM in Inhibiting Liver Fibrosis -- 6.2.1 Peach kernel extract combined with cordyceps can improve the activity of interstitial collugenase and enhance the reversion of liver fibrosis -- 6.2.2 Fuzheng Huayu Recipe can reverse liver fibrosis in chronic hepatitis B and has comprehensive effect on post-hepatitic cirrhosis -- 6.2.3 861 recipe (comprised of 10 herbs such as mongolian milkvetch root, salvia root, suberect spatholobus stem, etc.) -- 6.2.4 Salvia root and its effective ingredients -- 6.3 Multi-Link and Multi-Level Comprehensive Anti-Liver Fibrosis Mechanism of Chinese Herbs -- 6.3.1 Inhibiting fibre proliferating stimulating factor, HSC proliferation, TGF 1 and collagen mRNA expression -- 6.3.2 Anti-liver injury, protecting hepatocyte and improving the recovery of chronic liver injured cells -- 6.3.3 Action of compound recipe of Chinese herbs on inhibiting hepatic sinusoidal capillarisation -- 6.3.4 Action mechanism of salvianolic acid B(SA-B) (effective anti-liver fibrosis ingredient of salvia) on TGF- 1 intracellular signal transduction -- References -- Chapter 7 Advances in the Treatment of Lung Cancer by Traditional Chinese Medicine Jia-xiang Liu -- 7.1 Introduction -- 7.2 Aetiology and Pathogenesis -- 7.3 Clinical Trial.

7.3.1 Study on therapeutic effect and its assessment standard -- 7.3.2 Study on treatment based on syndrome differentiation -- 7.3.3 Study on therapeutic principles and specific prescriptions -- 7.3.4 Study on new drugs and agents -- 7.3.5 Study on therapy of combination of TCM and Western medicine -- 7.4 The Experience and Future Prospects -- References -- Chapter 8 Direction of TCM Modernisation and Quality Control Mode Pei-shan Xie & Eric Wong -- References -- Chapter 9 A Critical Look at Traditional Medicine Recommendations in the Line of Research Approach Ping-chung Leung -- 9.1 Introduction -- 9.2 Evidence on the Efficacy of TM-CAM -- 9.2.1 History of TM-CAM -- 9.2.2 Archives on TM-CAM -- 9.2.3 Current modern literature -- 9.2.4 Current practices -- 9.2.5 Herb-derived pharmaceuticals -- 9.3 Major Challenges to the Evidence of Efficacy of TM-CAM -- 9.3.1 Past archives might not be reliable -- 9.3.2 Clinical efficacy needs to be proven with modern methodology -- 9.4 Setting Up a System of Research for Evidence-Based Efficacy of TM-CAM -- 9.4.1 Set the priority areas -- 9.4.2 The efficacy driven approach -- 9.5 Conclusion and Recommendations -- Recommendations -- References -- Chapter 10 Study of XS0601 on Preventing Restenosis after Coronary Interventional Treatment Ke-ji Chen, Hao Xu, Da-zhuo Shi & Xiao-chang Ma -- 10.1 Introduction -- 10.2 Methods -- 10.2.1 Clinical study -- 10.2.1.1 Diagnostic criteria -- 10.2.1.2 Patient selection and inclusion and exclusion criteria -- 10.2.1.3 Treatment protocol -- 10.2.1.4 Clinical and angiographic end-points -- 10.2.2 Experimental study -- 10.2.2.1 Animals -- 10.2.2.2 Experimental protocol -- 10.2.2.3 Morphometric analysis -- 10.2.2.4 Transmission electron microscopy -- 10.2.2.5 Angiographic analysis -- 10.2.3 Statistical analysis -- 10.3 Results -- 10.3.1 Clinical study.

10.3.1.1 Comparison of recurrent angina -- 10.3.1.2 Angiographic analysis -- 10.3.1.3 Comparison of clinical events -- 10.3.1.4 Comparison of BSSS between groups -- 10.3.1.5 Logistic regression analysis -- 10.3.2 Experimental study -- 10.3.2.1 Histopathological analysis -- 10.3.2.2 Morphometric analysis -- 10.3.2.3 Angiographic analysis -- 10.3.2.4 Relationships between acute gain, late lumen loss, intimal area and remodeling -- 10.3.2.5 Contribution of intimal hyperplasia and remodeling to late loss -- 10.4 Discussion -- Acknowledgements -- References -- Chapter 11 Research on Treatment of AIDS in Chinese Medicine Chong-fen Guan -- 11.1 Introduction -- 11.2 Clinical Research of Treating AIDS by CM -- 11.3 Experimental Research on CM for Anti-AIDS -- 11.3.1 Screening of anti-HIV drugs -- (1) Screening of single Chinese drugs and studies on their pharmacological function -- (2) Studies on effective components of Chinese drugs -- (3) Studies on CM compound prescriptions -- 11.3.2 Experimental research of Chinese medicine on models of AIDS -- 11.4 Conclusion -- References -- Chapter 12 Research and Production of Dachengqi Granules Xian-zhong Wu, Zai-shan Tian & Chang Chen -- 12.1 Introduction -- 12.2 Background of Clinical Investigation and Experimental Research of Dachengqi Granules -- 1. As a main therapeutic principle in acute intestinal obstruction -- 2. Purgation combined with other therapies used in abdominal inflammations -- (a) Severe acute pancreatitis (SAP) -- (b) Acute severe cholangitis (ASC) -- 3. Application of purgation in systemic inflammatory reaction syndrome (SIRS)/multiple organ deficiency syndrome (MODS) caused by severe abdominal infection -- 4. Pre-operative application of Danchengqi granules -- 5. Experimental study of Dachengqi decoction -- 12.3 Research and Production of Dachengqi Granules.

12.4 Pharmacological and Toxicological Studies -- References -- Chapter 13 Study on Evacuation of Haematoma and Traditional Chinese Medical Therapy in Hypertensive Middle- and Large- Amount of Cerebral Haemorrhage Mao-cai Liu, Pei-xin Huang, Yan Huang & Ming Lu -- 13.1 Introduction -- 13.2 Thoughts of Study -- 13.2.1 Therapeutic status quo and analysis -- 13.2.2 Necessity and principles of comprehensive therapeutic protocols -- 13.3 Scheme of Study -- 13.3.1 Selection of subjects -- 13.3.2 Therapeutic protocol -- (1) Surgical Operation -- (2) Chinese Herbal Therapy -- (a) Establishment of Therapeutic Principle -- (b) Selection of Chinese Herb -- (c) Basic Treatment and Expectant Managements -- 13.4 Clinical Investigation -- 13.4.1 Investigation on treating 201 cases with HMLCH by comprehensive therapeutic treatment of TCM integrated with western medicine -- (1) Clinical materials -- (a) Source of Cases -- (b) Selection of Cases -- (c) General Conditions: a simple randomised control trial was applied in 201 cases, with 103 cases in the treatment group (T group) and 98 cases in the control group (C group) -- (d) Comparability Test Before Treatment -- (2) Therapeutic methods -- (a) Treatment group: comprehensive therapeutic protocols -- (b) The control group -- (c) Standards of clinical effect assessment -- (d) Results -- 13.4.2 Effect of Naomai II capsules on cerebro-cardiac syndrome caused by cerebral haemorrhage -- 13.4.3 Influence of rectal drip with Tongfu Xinshen liquid on situations of consciousness in patients with coma secondary to haemorrhagic stroke -- 13.5 Laboratory Study -- 13.5.1 Study of Tongfu Xinshen capsules, Naomai II capsules and Naomai I capsules on the possible precautionary and therapeutic mechanism in rat with cerebral haemorrhage.

13.5.2 Study of Zhongfeng Jiedu decoction on the possible precautionary and therapeutic mechanism in rat with cerebro-visceral syndrome secondary to cerebral haemorrhage.